Novel Derivative For Dithiocarbamite Containing A New Sulphur-Azo Linkage And Its Complexes With Sn(II), Sn(IV), Co(II), Ni(II) And Cu(II) Ions; Synthesis, Characterization and Antibacterial Activity

Abstract

The new ligand N-methyl-N-((((4-nitrophenyl)diazenyl)thio) carbonothioyl) aniline (LS2) was prepared by the reaction of 4-nitrobenzenediazonium salts with a (sodium N-methyl- N-phenyldithiocarbamate), a new ligand containing azo-sulphur linkage. A series of metal ions Sn(II), Sn(IV), Co(II), Ni(II), and Cu(II) were used to prepare metal complexes through reaction of two moles of LS2 ligand with one mole of appropriate metal chloride. The prepared compounds were characterized by CHNS elemental analysis, infrared spectroscopy (FT-IR), 1H NMR-spectroscopy, mass spectroscopy, UV-visible spectroscopy, magnetic susceptibility, and conductivity measurements. Stoichiometry was determined using analytical and spectroscopic information and it was found to be 1:2 (metal to a ligand) for all complexes. The spectral data confirm the coordination of the LS2 ligand with all metal ions through sulfur atoms of dithiocarbamate moiety. Molar conductivity of complexes was measured using DMF as a solvent and it was indicated that all prepared complexes were ionic. According to the results obtained from the elemental analysis and spectral measurements were complexes of Sn(II), Sn(IV) and Co(II) tetrahedral geometry, while the complexes with Ni(II) and Cu(II) had a square planar geometry. The ligand LS2 and its complexes were examined against Staphylococcus aurous bacteria and Escherichia coli bacteria.