Abstract
Injection of botulinum toxin is the most commonly performed nonsurgical cosmetic procedure worldwide. New applications and formulations of botulinum toxin have become available for clinical use. This review presents recent advancements, applications, and new formulations of botulinum toxin. We also discuss issues regarding brand uniformity, safety, and patient satisfaction. Novel cosmetic uses for botulinum toxin include the treatment of androgenic alopecia, oily skin, and others. Two new toxin formulations include daxibotulinumtoxinA, with a duration of 6 months, and botulinum toxin E, with a fast onset of action (24 h) and duration of 2–4 weeks. Recent trends find increased usage among younger adults and men. Cosmetic injection of botulinum toxin into the head and neck remains an area of innovation and evolution. Research continues to support the finding that botulinum toxin formulations are equally safe and efficacious.
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