Abstract
Two cases of rapidly progressive acute respiratory infection in adults associated with a novel coronavirus have generated an international public health response. The two infections were acquired three months apart, probably in Saudi Arabia and Qatar. An interim case definition has been elaborated and was published on the World Health Organization website on 25 September 2012.
Highlights
Rapid communicationsNovel coronavirus associated with severe respiratory disease: Case definition and public health measures
Coronaviruses are globally distributed and are found in humans, other mammals and birds
Up to one third of mild upper respiratory tract infections in adults are caused by human coronaviruses
Summary
Novel coronavirus associated with severe respiratory disease: Case definition and public health measures. Two cases of rapidly progressive acute respiratory infection in adults associated with a novel coronavirus have generated an international public health response. On 13 June 2012 a patient in their sixties presented with deteriorating pneumonia in Jeddah, Saudi Arabia and a seven day history of respiratory symptoms. A novel beta-coronavirus was isolated in Saudi Arabia* and sequenced at the Erasmus Medical Centre (EMC) in Rotterdam, the Netherlands [1]. Some of them have reported mild respiratory symptoms but none have tested positive for the novel virus or developed severe disease to date [3]
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