Novel chitosan-based bone substitute. A summary of in vitro and in vivo evaluation

Abstract

Backgorund: Composite bone substitute materials have been raising more interest as an alternative for autologous transplants and pure xenogenic materials in oral surgery for last few years. These not immunogenic and completely resorbable biomaterials may become the basis for complete and predictable guided bone regeneration. In the majority of cases the deciding factor is ease of application of the material by a surgeon.