Abstract

Polycystic ovary syndrome (PCOS) is an alarming gynaecological endocrine disorder affects women of reproductive age. Hyperandrogenism contributes for a cluster of cardio-metabolic risk factors characterized by reproductive dysfunction, polycystic ovaries, anovulation, and cosmetic dysfunctions. Although during the past decades, substantial research efforts tried to uncover the exact aetiology and pathogenesis of PCOS but owing to the complex etiology, the patho-physiological mechanisms of PCOS remains in doubt. To develop potential and highly efficient therapeutic strategies, there are many proteins which can act as potential biomarkers for PCOS. These biomarker proteins and enzymes may involve in the early detection and handling of this condition and mitigate the risk of long-term problems.

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