Novel Approach Self Nanoemulsifying Drug Delivery System: A Review

Abstract

The self-nanoemulsifying drug delivery system is solitarily the most frequent dosage form for administering drug molecules towards the target region in the pharmaceutical industry. It has gotten a lot of interest in the current scenario because of its budding applications in various industries. In the pharmaceutical business, self-nanoemulsifying drug delivery systems have been used to distribute medications via oral, topical, and parenteral routes. SNEDDS are submicron-sized emulsions being researched as drug carriers to improve therapeutic agent delivery. Due to their tiny droplets, elevated solubility ability, broad interfacial region, reduced consistency, transparent or semi-transparent emergence, & remarkable kinetic constancy, self-nanoemulsifying medicines are meant for an extensive choice of application. Through a combination of a water-insoluble lipid phase with a high-stress aqueous phase, these emulsions may be manufactured in huge quantities quickly. These are created using surfactants, co-surfactants, and co-solvents. In BCS class II and IV drugs, the self-nanoemulsifying drug delivery system is useful in favor of increasing the water solubility of water-soluble pharmaceuticals. In this review, various aspects of the self-nanoemulsifying drug delivery system are highlighted, including method of preparation, characterization techniques such as particle size, zeta potential, polydispersity, drug content, advantages, disadvantages, and a particular importance on various applications of SNEDDS in different areas, such as cancer treatment, drug targeting, and as a vehicle for transdermal drug delivery.