Abstract

AbstractEthyl 3‐amino‐4,4,4‐trifluorocrotonate (3) has been converted by a one step reaction with alkyl and aryl isocyanates to novel 3‐substituted‐6‐(trifluoromethyI)uracils. Also several 3‐amino‐4,4,4‐trifluorocrotonitriles (11a‐c) have been cyclized to novel 6‐(trifluoromethyI)cytosines (13a‐c) and then hydrolyzed to the corresponding uracils (4, 14b‐c). Alkylation studies with isopropyl bromide of three 6‐(trifluoromethyl)uracils (1, 4, 5) are described.

Full Text
Paper version not known

Talk to us

Join us for a 30 min session where you can share your feedback and ask us any queries you have

Schedule a call