Abstract

According to Matsuki, the first report about the intrathecal (IT) use of morphine for pain relief was by the Japanese surgeon Otojiro Kitagawa, on April 2, 1901. While doing a bibliographical research about the history of spinal anesthesia (SA) in Chile, I found some interesting data in a communication about Intraspinal Injections of Cocaine, published in Revista Médica de Chile, September 1901. In that paper, Dr. Caupolicán Pardo states that the French surgeon Mathieu Jaboulay from Lyon reported in 1899 the IT use of a mixture of cocaine and morphine for relieving cancer pain. After that discovery, and reviewing Matsuki's publication where the first page of Kitagawa's paper is reproduced, I found the name Jaboulay mentioned on that page, so he must have known Jaboulay's work. So a French, not a Japanese, was the first to report the use of IT morphine for pain relief in man.

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