Abstract
Recent refinements in the nomenclature have attempted to simplify previous classification schemes regarding acute pancreatitis and its sequelae. Our understanding of the natural history of acute pancreatitis and its sequelae continues to evolve. A subset of patients with acute pancreatitis develops peripancreatic collections that, over time, may evolve into walled-off necrosis (WON). The currently available literature suggests that endoscopic management of WON is the preferred management strategy in the majority of cases. Treatment strategies range from simple drainage of liquefied contents to repeated direct endoscopic necrosectomy (DEN) of a complex necrotic collection, with each method requiring a variety of techniques and tools necessary to achieve success. In this chapter, we focus on the indications, techniques, and outcomes for endoscopic therapy of WON.
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