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Abstract
Toxic epidermal necrolysis (TEN) is a severe mucocutaneous adverse reaction, potentially life threatening, which occurs mainly due to drugs and involves more than 30% of the body surface area. Here, we report an extremely rare case of TEN secondary to itraconazole developing in a young female who was prescribed itraconazole for tinea cruris with corporis. Cutaneous side effects of itraconazole are rare and usually mild. It can manifest as maculopapular rash, xed drug eruption, urticaria and angioedema. But development of TEN secondary to itraconazole is extremely uncommon and rarely implicated as a culprit drug for TEN. In countries with high prevalence of tinea cruris and corporis, dermatologists and clinicians should be aware about the possibilities of adverse reactions that can occur due to itraconazole.
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