Abstract
Good syndrome (GS) is a hypogammaglobulinemia associated with the presence of a thymoma. Patients with GS often are adults who present with recurrent upper respiratory tract infections and anterior mediastinal masses. GS has no formal diagnostic criteria. The syndrome is defined most commonly as a thymoma plus humoral and cellular immune deficiency. The cause of GS is not known. The primary clinical manifestations of GS are caused by the immunodeficiency. Patients with GS are susceptible to a wide range of infections. Treatment of GS consists of thymectomy and immunoglobulin replacement with intravenous immunoglobulin.
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