Not in the Year 2525 …︁

Asia—Growing Stronger

New Members of the Editorial Board and International Advisory Board of <i>Angewandte Chemie</i>

In Good Company

All Good Things Come in Threes…︁

As we have witnessed over the past several years, research in Asia is growing at an exciting pace and is making an ever-increasing impact in the global scientific community. This is evidenced, for example, by the astonishing increase in published articles from Asia in top international journals such as Angewandte Chemie, Chemistry—A European Journal, Journal of the American Chemical Society, and, of course, Chemistry—An Asian Journal. I am pleased to see that the initial vision of Chemistry—An Asian Journal has come to fruition. Thanks to the joint efforts of its Editorial Board, International Advisory Board, and editorial staff, as well as the individual Asian Chemical Editorial Society (ACES) members and the publisher Wiley-VCH, Chemistry—An Asian Journal has quickly established itself as a leading “full paper venue” for disseminating the best of both Asian and international research. Over its first two years, our journal has published a constant flow of high-quality Full Papers and timely Focus Reviews while maintaining the highest scientific standards with a rejection rate of about 60%. Submissions to Chemistry—An Asian Journal have been steadily climbing over the journal's first two years, particularly from ACES member countries, and ever more authors in general are opting to publish their results as Communications with Supporting Information. In response to these upward trends as well as considerable feedback from the chemistry community and unified support from the owner societies, it is time for the journal to take the next step and offer a broader range of article types. In January 2009, Chemistry—An Asian Journal will launch a Communication section in addition to its Full Paper and Focus Review sections. Submissions of Communications are already being accepted, and guidelines for the preparation of manuscripts can be found at the journal homepage (www.chemasianj.org). The combination of a Communication and Full Paper section is a natural balance: Chemistry—A European Journal, our sister journal, began publishing Communications in January 2008 to complement its highly successful Full Paper section, and the Journal of the American Chemical Society also has a combination of Full Papers and Communications. With this new addition, Chemistry—An Asian Journal will be able to offer rapid dissemination of urgent results while still publishing comprehensive original articles. Everyone would surely agree that Communications in general are crucial for the scientific literature to keep pace with rapid developments in research, but I would like to take this opportunity to emphasize the vital importance of also writing Full Papers particularly for Asian chemists. From my own personal observations, I would say that although the Asian chemical community has recently made tremendous strides, it is still not yet fully matured as a whole. In some countries, under the pressure of governmental or other evaluation agencies, young researchers often concentrate too much on publishing papers that are too easy, just for the purpose of “scoring points” on their publication list. I am very much disappointed at this situation. Their papers are too technical and do not offer enough conceptual insight or detail. Such robotic production of cheap, technical notes should be avoided. Furthermore, no benefit is gained by the overuse of catchy titles and self-promotional buzz terms such as “new paradigm”, “strategy”, “innovation”, “novel”, or “remarkably efficient”. Scientific journals should be attractive for researchers, but they should also be readable. These days, far too many journals exist only for the sake of their authors and publishers and seem to have lost sight of the real target of their publishing activities: their readers who are engaged in serious scientific research! Chemistry—An Asian Journal has a role to play in nurturing talented chemists in Asia, but this can only be achieved through the cooperation of our scientific community and the publishing house. There is an overriding tendency for Asian chemists to submit Communications rather than Full Papers, owing in part to linguistic limitations. But with the availability of editing services as well as assistance from multinational colleagues and the help of editorial staff at the publisher, language should not be used as an excuse. I strongly encourage young Asians to make a habit of writing well-thought-out scholarly Full Papers that tell a scientific “story”. Only by providing such depth in conveying their results will young researchers ever gain a solid reputation and become influential in the community. A short Communication with tables, figures, schemes, and a few brief sentences is not sufficient to disclose an author's important scientific philosophy. Supporting Information does not help either. For the sake of their own professional development, researchers should be judicious in deciding which results to publish as short Communications, and it is essential to keep these in a proper balance with more-comprehensive Full Paper submissions. I am encouraged that Chemistry – An Asian Journal is continuing in its role as the best arena for nurturing thoughtful young chemists. 1 1

Cooperative Effect

<i>ChemNanoMat</i>-A New Journal for Small Science with a Big Impact

For the Chinese, the number 3 is an auspicious one, because it symbolizes birth and life. And as Chemistry—An Asian Journal begins its 3rd volume, all the signs are that it is indeed alive and well in the international chemistry community. In Asia, in particular, Chemistry—An Asian Journal has been extremely well-received. The journal was conceived as a world-class platform for Asian chemists to publish their best research, and they have embraced it whole-heartedly. Figure 1 shows the origin of the manuscripts published in 2007, highlighting the large proportion of Asian chemistry that has been showcased. Science, however, is not limited by race or nationality, and the journal has also published many papers by authors around the world (Figure 1). The international nature of the journal is exemplified by the highly popular inclusion of abstracts in the native language of the authors: abstracts in Chinese, Japanese, Korean, Hindi, German, Swedish, and Polish, to name a few, have been published. Geographical distribution of accepted manuscripts (January–October 2007). The success of a journal is not just measured by the response of authors, but also by that of its readers. Chemistry—An Asian Journal will only receive its first impact factor for 2008; even before that, it has already made its mark among readers, judging by citations in top journals and the number of downloads so far. The 10 most-downloaded articles for 2007 are shown in Table 1. It is an excellent sign that the normalized average value for the full-text downloads per article for Chemistry—An Asian Journal is identical to that of our sister journal Chemistry—A European Journal. Author Title Reference 1. M. Shibasaki et al. Total Synthesis of Lactacystin and Salinosporamide A 2007, 2, 20–38. 2. S. Kamijo and Y. Yamamoto Recent Progress in the Catalytic Synthesis of Imidazoles 2007, 2, 568–578. 3. T. Mukaiyama et al. Enantioselective Synthesis of 3,4-Dihydropyran-2-ones by Domino Michael Addition and Lactonization with New Asymmetric Organocatalysts: Cinchona-Alkaloid-Derived Chiral Quaternary Ammonium Phenoxides 2007, 2, 123–134. 4. M. Fujita et al. Self-Assembly and Host–Guest Chemistry of a 3.5-nm Coordination Nanotube 2007, 2, 468–476. 5. S.-L. You Recent Developments in Asymmetric Transfer Hydrogenation with Hantzsch Esters: A Biomimetic Approach 2007, 2, 820–827. 6. Z.-T. Li et al. Shape-Persistent Aromatic Amide Oligomers: New Tools for Supramolecular Chemistry 2006, 1, 766–778. 7. Q. Peng, Y. Li et al. Nd-Doped TiO2 Nanorods: Preparation and Application in Dye-Sensitized Solar Cells 2006, 1, 737–741. 8. J. F. Stoddart et al. Toward Electrochemically Controllable Tristable Three-Station [2]Catenanes 2007, 2, 76–93. 9. A. Dondoni Triazole: the Keystone in Glycosylated Molecular Architectures Constructed by a Click Reaction 2007, 2, 700–708. 10. H. Yamamoto et al. Silver-Catalyzed Asymmetric Allylation: Allyltrimethoxysilane as a Remarkable Reagent 2007, 2, 692–698. The success of Chemistry—An Asian Journal is a reflection of the close cooperation between the member societies of ACES (Asian Chemical Editorial Society), which recently held its third meeting in Bangalore, India. Ties were strengthened and new links were formed. The members undertook to support the new sister journal, ChemSusChem, thus strengthening the collaboration with the European chemical societies. The society representatives also pledged continued support for Chemistry—An Asian Journal and would keep on encouraging their members to submit their best manuscripts to Chemistry—An Asian Journal. Three new member societies joined ACES last year: The Hong Kong Chemical Society, the Royal Australian Chemical Institute, and the Chemical Society of Thailand. More are still to come. The next ACES meeting will be held in the summer of 2008 in Seoul, South Korea. Looking ahead in 2008, Chemistry—An Asian Journal will continue to deliver high-quality Full Papers and interesting and topical Focus Reviews in each issue. This issue alone contains a VIP (qualified as a Very Important Paper by two referees) as well as five papers by members of the Editorial and International Advisory Boards. In addition, the next issue will be a special one in honor of Professor Teruaki Mukaiyama, one of the greatest organic chemists of our time. The response to contribute to this special issue has been exceptional, and we can expect to see many top-notch, cutting-edge research papers from some of the best organic chemists in the world (see Table 2). Author Title 1. B. M. Trost and A. McClory Metal Vinylidenes as Catalytic Species in Organic Reactions (Focus Review) 2. S. Kobayashi et al. Immobilized Metal Catalysts for Environmentally Benign Oxidation of Alcohols (Focus Review) 3. I. Paterson et al. Total Synthesis of (-)-Reidispongiolide A, an Actin-Targeting Macrolide Isolated from the Marine Sponge Reidispongia Coerulea 4. K. Maruoka et al. Asymmetric 1,3-Dipolar Cycloaddtions of N-Benzyl and N-Diphenylmethyl Nitrones and α,β-Unsaturated Aldehydes Catalyzed by Bis-Titanium Chiral Lewis Acids 5. M. Shibasaki, S. Matsunaga et al. Chiral-Catalyst-Based Convergent Synthesis of HIV Protease Inhibitor GRL-06579A 6. M. T. Reetz and D. Kahakeaw A Cell-Based Adrenaline Assay for Automated High-Throughput-Screening of Epoxide Hydrolases 7. M. Inoue, N. Hirama et al. Synthesis of the Bicyclo[7.3.0]dodecadiyne Core of the Maduropeptin Chromophore 8. Y. Hayashi et al. Direct Asymmetric α-Amination of Cyclic Ketones Catalyzed by Siloxyproline 9. Y. Kishi et al. Unique Reactivity of the Mukaiyama Glycosidation Catalyst (SnCl3ClO4) toward β-Mannopyranosides 10. M. Yamaguchi et al. Reversible Double Helix–Random Coil Transition Process of Bis{hexa(ethynylhelicene)}s 11. A. Fürstner and A. Korte Total Synthesis of Epohelmin B and Analogues 12. T. Fukuyama et al. Total Synthesis of (+)-Yatakemycin 13. K. C. Nicolaou, D. Y.-K. Chen et al. Total Syntheses of Thiopeptide Antibiotics GE2270A, GE2270T, and GE2270C As Chemistry – An Asian Journal enters its 3rd year in 2008, it is my hope that the journal will continue to bring chemists of the diverse regions of Asia together, and that authors and readers alike will continue to maintain its success. I wish Chemistry – An Asian Journal a successful third year and a long and prosperous life. 1 Fu Xi Chairman of ACES (Asian Chemical Editorial Society) P. S. Our sister publication Chemistry—A European Journal will start publishing Communications from 2008. Please note that authors can submit Short Full Papers, which in essence are longer Communications, to Chemistry—An Asian Journal. These Short Full Papers are especially welcome and will be fast-tracked. Professor Fu Xi was born in 1939 and obtained his BSc from the University of Beijing in 1962. He is a Professor at the Institute of Chemistry of the Chinese Academy of Sciences and is Vice-President of the Chinese Chemical Society. He has been a Visiting Scholar at the Department of Polymer Science and Engineering of the University of Massachusetts and at the Department of Chemistry of the Polytechnic University. His research interests include the synthesis and architecture of functional polymers, hyperbranched polymers, and dendrimers as well as molecular assembly and self-assembly.

Editorial: Onwards and Upwards-The Future Is Bright for Chemistry!

Fertile Ground

Who Is Going to Read all This?

Hungarian Rhapsody: 1st Movement Comes to a Close

Extensive coverage: 1 Chemistry—A European Journal has provided its readers with crystal-clear top-quality chemistry from around the world since it was founded 15 years ago. Originally launched as a monthly journal for Full Papers, Chemistry—A European Journal has since made the successful transition to a weekly publication, offering its readers in addition a wide range of article types, including Concepts, Communications, Reviews, and Minireviews. The growth over this period in terms of articles published is truly remarkable (see Figure 1): in 2009 we published 1435 top-quality articles on over 13 500 pages. In 2008 we launched the Communications section of the journal; in the first year we published 167 Communications. Last year the number of Communications published more than doubled to 370, and the number of Full Papers published also grew by more than 6 % to over 1000. Growth of Chemistry—A European Journal in terms of the number of articles since its launch in 1995. The move to weekly publication has been accompanied by not only a marked increase of over 30 % in the number of submissions to the journal, but also more importantly by a 22 % increase in the number of peer-reviewed published articles. Pleasingly, the Impact Factor for Chemistry—A European Journal rose for the sixth consecutive year to a new record level of 5.454 in 2009. Internationalization: The global influence of Chemistry—A European Journal is reflected not only by the number of submissions, but also by the fact that we received papers from over 60 countries in 2009. The major increases in the number of submissions from Asia came from Taiwan (+96 %), South Korea (+63 %), China (+29 %), Japan (+27 %), and India (+38 %). In Europe the main growth came from Denmark (93 %), Italy (+35 %), Spain (+34 %), Switzerland (+34 %), France (+22 %), and Germany (+20 %). There was also notable growth in the number of submissions from North America (USA +31%; Canada +52 %), and in the Rest of the World there was a dramatic increase in the number of submissions from Australia (80 %). Growing influence: Over the last 10 years the global distribution of submissions and accepted papers has altered considerably (see Figure 2). Chemistry—A European Journal, like most other top ranking journals, has witnessed the growing influence of chemistry from Asia, both in terms of output and improving quality. This is also reflected in the increasing number of papers from Asian universities that appear regularly among the most downloaded publications in the journal. Internationalization of Chemistry—A European Journal: regional breakdown of papers submitted (right) and correspondence authors (left) of papers published in Chemistry—A European Journal in 2001, 2005, and 2009. Submitted data for 2009 extrapolated from data on November 30, 2009. Our sister journal, Chemistry—An Asian Journal, is testimony to this growing influence. The announcement of its first impact factor of 4.197 in 2009 was followed by a dramatic increase in the number of top papers submitted from the partner societies. The ACES partnership behind Chemistry—An Asian Journal, which also supports Chemistry—A European Journal, also gained a new member during the course of 2009, with the Chemical Society of Vietnam joining the growing ranks of its society partners. There are now 12 member chemical societies of the ACES partnership. These together with the 14 members of ChemPubSoc Europe provide a further illustration of the strength of the commitment of Wiley-VCH to promoting chemical sciences and chemical societies. The ChemPubSoc Europe family of journals, which encompasses 1 the European Journal of Organic Chemistry, the European Journal of Inorganic Chemistry, ChemPhysChem, ChemBioChem, ChemMedChem, and ChemSusChem, was extended in 2009 by the addition of its newest member ChemCatChem. This journal has made an excellent start and the first issues are freely available online (see www.chemcatchem.org for details). ChemPubSoc Europe itself is expanding to include “Supporting Societies”, the first of which is the Slovenská chemická spoločnost' (SCHS).1 A Nobel occasion: As part of the celebrations to mark the 10th anniversary of our sister journals ChemPhysChem and ChemBioChem, there will be a symposium entitled “Frontiers of Chemistry: From Molecules to Systems” at the Maison de la Chimie in Paris on May 21, 2010. 1 This special event will feature lectures from four Nobel Laureates: Gerhard Ertl, Jean-Marie Lehn, Roger Tsien, and the 2009 winner Ada Yonath. Further details of the program and the other keynote speakers can be found under www.chembiophyschem.org. European showcase for chemistry: Europe will again be a prominent stage in the world of chemistry in 2010 with the 3rd EuCheMS Chemistry Congress (Chemistry—The Creative Force) providing a notable highlight of the upcoming year. The event, which is being organized by the German Chemical Society (GDCh) on behalf of EuCheMS, will take place in Nürnberg, Germany, between August 29 and September 2, 2010. 1 The Congress will cover seven main topics, each of which will host three symposia: Innovative Materials; Resources and Environment; Supramolecular Systems; Catalysis; Molecular Life Sciences; Analysis, Manipulation and Simulation; and Advances in Organic and Inorganic Chemistry. The program, which features top speakers from all around the world, has been put together by François Diederich and Andreas Hirsch, the chairmen of the event, and the 21 symposia conveners. Further details can be found under www.euchems- congress2010.org. Special effects: As part of our continued mission to promote the aims and science of our society partners, we produced a special issue marking the 100th anniversary of the Società Chimica Italiana (Italian Chemistry Society). In addition to numerous Communications and Full Papers from top Italian chemists, the issue featured some fascinating historical articles about the key figures in the development of Italian chemistry and the Italian Chemical Society, as well as a guest editorial from Professor Luigi Campanella, the President of the society. 1 The special issue was also made available at a conference (“The Centenary”) in Padova to mark the event. It proved to be highly successful, and we would to thank all Italian authors who contributed. We also produced a special issue to mark the 65th birthday of Professor Yitzhak Apeloig, whose research interests span organic to silicon and computational chemistry. Professor Apeloig, incidentally, will be giving one of the lectures at the 3rd EuCheMS Chemistry Congress in Nürnberg. The place to be: In the first 15 years of Chemistry—A European Journal, we have published 357 issues of the journal, in which over 9000 papers have appeared: 467 Concepts and Reviews, 8112 Full Papers, and 437 Communications. Over the course of this period we delivered our readers over 92 000 pages packed with top-quality chemistry. The most cited papers in this 15-year period are given in Table 1. Top of the class at present is a paper by Frank Caruso entitled “Hollow Capsule Processing through Colloidal Templating and Self-Assembly”. A fairer assessment of the citations of the papers we have published can be made, however, if one considers the average number of citations per year (see Table 2). In this case the paper by Younan Xia and co-workers, entitled “Shape-Controlled Synthesis of Metal Nanostructures: The Case of Silver” was determined to be the most prominent. The other papers featured in these two tables illustrate the diversity and quality of the papers published in Chemistry—A European Journal. Title Authors Citation Cites Hollow Capsule Processing through Colloidal Templating and Self-Assembly F. Caruso Chem. Eur. J. 2000, 6, 413 464 Maximizing Synthetic Efficiency: Multi-component Transformations Lead the Way H. Bienayme et al. Chem. Eur. J. 2000, 6, 3321 418 Dynamic Combinatorial Chemistry and Virtual Combinatorial Libraries J.-M. Lehn Chem. Eur. J. 1999, 5, 2455 379 Organic Fluorine Hardly ever Accepts Hydrogen Bonds J. D. Dunitz, R. Taylor Chem. Eur. J. 1997, 3, 89 359 Light-Triggered Molecular Devices—Photochemical Switching of Optical and Electrochemical Properties in Molecular Wire Type Diarylethene Species J. M. Lehn et al. Chem. Eur. J. 1995, 1, 275 336 Palladacycles: Efficient New Catalysts for the Heck Vinylation of Aryl Halides W. A. Herrmann et al. Chem. Eur. J. 1997, 3, 1357 313 Functional Dendrimers: Unique Biological Mimics D. K. Smith, F. Diederich Chem. Eur. J. 1998, 4, 1353 312 Double-Stranded Helices and Molecular Zippers Assembled from Single-Stranded Coordination Polymers Directed by Supramolecular Interactions X.-M. Chen, G. F. Liu Chem. Eur. J. 2002, 8, 4811 298 Shape-Controlled Synthesis of Metal Nanostructures: The Case of Silver Y. Xia et al. Chem. Eur. J. 2005, 11, 454 290 Synthesis and Characterization of Ion-Exchangeable Titanate Nanotubes X.-M. Sun, Y.-D. Li Chem. Eur. J. 2003, 9, 2229 290 Title Authors Citation Average cites per year Shape-Controlled Synthesis of Metal Nanostructures: The Case of Silver Y. Xia et al. Chem. Eur. J. 2005, 11, 454 58.0 Hollow Capsule Processing through Colloidal Templating and Self-Assembly F. Caruso Chem. Eur. J. 2000, 6, 413 46.4 Synthesis, X-ray Crystal Structures, and Gas Sorption Properties of Pillared Square Grid Nets Based on Paddle-wheel Motifs: Implications for Hydrogen Storage in Porous Materials K. Kim et al. Chem. Eur. J. 2005, 11, 3521 46.2 Organocatalysis Mediated by (Thio)urea Derivatives S. J. Connon Chem. Eur. J. 2006, 12, 5418 44.3 Phosphorescent Dyes for Organic Light-Emitting Diodes P. T. Chou, Y. Chi Chem. Eur. J. 2007, 13, 380 42.7 Maximizing Synthetic Efficiency: Multi-component Transformations Lead the Way H. Bienayme et al. Chem. Eur. J. 2000, 6, 3321 41.8 Synthesis and Characterization of Ion-Exchangeable Titanate Nanotubes X.-M. Sun, Y.-D. Li Chem. Eur. J. 2003, 9, 2229 41.3 Detection and Amplification of Chirality by Helical Polymers E. Yashima et al. Chem. Eur. J. 2004, 10, 42 40.3 Double-Stranded Helices and Molecular Zippers Assembled from Single-Stranded Coordination Polymers Directed by Supramolecular Interactions X.-M. Chen, G. F. Liu Chem. Eur. J. 2002, 8, 4811 37.3 Molecular-Scale Logic Gates A. P. de Silva, N. D. McClenaghan Chem. Eur. J. 2004, 10, 574 37.2 Metal Nuclearity Modulated Four-, Six-, and Eight-Connected Entangled Frameworks Based on Mono-, Bi-, and Trimetallic Cores as Nodes E. B. Wang, Z.-M. Su et al. Chem. Eur. J. 2006, 12, 2680 36.8 What's hot: A selection of the top 5 downloaded Full Papers and Communications, as well as the top 10 downloaded Concepts and Reviews from 2009 is given in Tables 3–, , 5. The data in the tables again illustrate the international appeal and authorship of the journal, as well as the diverse range of topics covered. The importance and interest in catalysis is clearly apparent from the list of the top 5 downloaded Communications in Table 3. This serves as a further illustration of the perfect timing of the decision by ChemPubSoc Europe to launch ChemCatChem. Title Authors Citation Asymmetric Iminium Ion Catalysis with a Novel Bifunctional Primary Amine Thiourea: Controlling Adjacent Quaternary and Tertiary Stereocenters P. Melchiorre et al. Chem. Eur. J. 2009, 15, 7846 Iron(III)-Catalyzed and Air-Mediated Tandem Reaction of Aldehydes, Alkynes and Amines: An Efficient Approach to Substituted Quinolines Y.-Q. Tu et al. Chem. Eur. J. 2009, 15, 6332 Highly Enantio- and Diastereoselective Organocatalytic Desymmetrization of Prochiral Cyclohexanones by Simple Direct Aldol Reaction Catalyzed by Proline R. Rios et al. Chem. Eur. J. 2009, 15, 6564 Iron-Catalyzed Ligand-Free Three-Component Coupling Reactions of Aldehydes, Terminal Alkynes, and Amines L. Wang et al. Chem. Eur. J. 2009, 15, 2045 Improved Palladium-Catalyzed Sonogashira Coupling Reactions of Aryl Chlorides M. Beller at al. Chem. Eur. J. 2009, 15, 1329 Title Authors Citation Organocatalytic Domino Michael–Knoevenagel Condensation Reaction for the Synthesis of Optically Active 3-Diethoxyphosphoryl-2-oxocyclohex-3-enecarboxylates K. -A. Jørgensen et al. Chem. Eur. J. 2009, 15, 3093 Total Synthesis of Rapamycin S. V. Ley et al. Chem. Eur. J. 2009, 15, 2874 Novel Zinc Porphyrin Sensitizers for Dye-Sensitized Solar Cells: Synthesis and Spectral, Electrochemical, and Photovoltaic Properties C.-Y. Yeh, E. W.-G. Diau et al. Chem. Eur. J. 2009, 15, 1403 One-Step Synthesis of Stoichiometrically Defined Metal Oxide Nanoparticles at Room Temperature M. A. Morris et al. Chem. Eur. J. 2009, 15, 440 Bright, Color-Tunable Fluorescent Dyes in the Vis/NIR Region: Establishment of New “Tailor-Made” Multicolor Fluorophores Based on Borondipyrromethene K. Suzuki et al. Chem. Eur. J. 2009, 15, 1096 Title Authors Citation Metal-Catalyzed One-Step Synthesis: Towards Direct Alternatives to Multistep Heterocycle and Amino Acid Derivative Formation B. A. Arndtsen Chem. Eur. J. 2009, 15, 302 Artificial Enzyme Catalysis Controlled and Driven by Light G. Knör Chem. Eur. J. 2009, 15, 568 Do We Understand the Recyclability of Ionic Liquids? Y-M. Zhang, H.-P. Wang et al. Chem. Eur. J. 2009, 15, 1804 Construction of Nitrogen-Containing Heterocycles by CH Bond Functionalization M. Lautens, P. Thansandote Chem. Eur. J. 2009, 15, 5874 Use of Tetradentate Monoanionic Ligands for Stabilizing Reactive Metal Complexes J. Arnold, W. A. Chomitz Chem. Eur. J. 2009, 15, 2020 Diels–Alder “Click” Chemistry in Designing Dendritic Macromolecules A. K. Kakkar, G. Franc Chem. Eur. J. 2009, 15, 5630 Applications of Multicomponent Reactions to the Synthesis of Diverse Heterocyclic Scaffolds S. F. Martin, J. D. Sunderhaus Chem. Eur. J. 2009, 15, 1300 Structure Formation Principles and Reactivity of Organolithium Compounds C. Strohmann et al. Chem. Eur. J. 2009, 15, 3320 Radical and Radical-Ionic Multicomponent Processes Y. Landais, E. Godineau Chem. Eur. J. 2009, 15, 3044 Highly Enantioselective Synthesis of Linear β-Amino Alcohols J. Cossey et al. Chem. Eur. J. 2009, 15, 1064 The right mix: A summary of the top 10 downloaded articles from 2008 (Table 6) reveals that all the different article types, regardless of length, are attractive to our readers. The only important measure is the quality of the work presented. Title Authors Citation Type One-Pot Oxidative Esterification and Amidation of Aldehydes C. Wolf, K. Ekoue-Kovi Chem. Eur. J. 2008, 14, 6302 Review New Architectures for Dye-Sensitized Solar Cells J. T. Hupp et al. Chem. Eur. J. 2008, 14, 4458 Concept The Synthesis of Azadirachtin: A Potent Insect Antifeedant S. V. Ley et al. Chem. Eur. J. 2008, 14, 10683 Full Paper Iron-Catalyzed N-Arylations of Amides C. Bolm et al. Chem. Eur. J. 2008, 14, 3527 Communication Recent Developments in Enantioselective Gold(I) Catalysis R. A. Widenhofer Chem. Eur. J. 2008, 14, 5382 Concept Catalytic Asymmetric Synthesis of Chiral Phosphanes D. S. Glueck Chem. Eur. J. 2008, 14, 10683 Concept Classical Reagents: New Surprises in Palladium-Catalyzed CC Coupling Reactions T. Skrydstrup, A. T. Lindhardt Chem. Eur. J. 2008, 14, 8756 Concept New Strategies for the Synthesis of Pyrimidine Derivatives M. Movassaghi, M. D. Hill Chem. Eur. J. 2008, 14, 6836 Concept Recent Synthetic Applications of Manganese in Organic Synthesis J. M. Concellón et al. Chem. Eur. J. 2008, 14, 10184 Concept Facile Synthesis of Gold Nanoparticles with Narrow Size Distribution by Using AuCl or AuBr as the Precursor Y. Xia et al. Chem. Eur. J. 2008, 14, 1584 Full Paper Contented chemists: Over the last 15 years we have continually improved the service we offer to our referees, readers, and authors. We have implemented many novel innovations, such as Concepts, the online submission service, VIP papers, Frontispieces, and EarlyView, all of which have been well documented. These have helped to forge strong bonds and to encourage authors to publish their best work with us repeatedly on a regular basis. A list of the most prolific authors in the history of Chemistry—A European Journal is given in Table 7. A more recent reflection, which summarizes data for the last five years is given in Table 8; the most recent papers from several of these authors appear in this issue, for example, work by Atsuhiro Osuka et al. on phosphorus complexes of the first expanded isophlorins. These data provide further confirmation of the international appeal of the journal as well as the diversity of the fields which it covers. Among the newest improvements are inside covers, additional hot topics and virtual issues, as well as an effective network for facilitating the publication of articles within our family of journals. Name Country Number of articles J. Fraser Stoddart USA 62 Jean-Marie Lehn France 61 José Barluenga Spain 42 François Diederich Switzerland 38 David N. Reinhoudt The Netherlands 35 Chi-Ming Che China 36 Helmut Schwarz Germany 36 Gernot Frenking Germany 34 Armin de Meijere Germany 34 Vincenzo Balzani Italy 33 Herbert Waldmann Germany 32 Lutz F. Tietze Germany 31 Matthias Beller Germany 30 Klaus Müllen Germany 30 K. C. Nicolaou USA 30 Dirk M. Guldi Germany 29 Alois Fürstner Germany 28 E. W. Meijer The Netherlands 28 Atsuhiro Osuka Japan 28 Detlef Schröder Czech Republic 28 Name Country Number of articles Atsuhiro Osuka Japan 23 José Barluenga Spain 22 Gernot Frenking Germany 22 Jean-Marie Lehn France 20 Armin de Meijere Germany 18 François Diederich Switzerland 18 Chi-Ming Che China 17 Alois Fürstner Germany 17 Dirk M. Guldi Germany 17 Matthias Beller Germany 16 Helmut Schwarz Germany 16 Luis Echegoyen USA 15 Shunichi Fukuzumi Japan 15 Min Shi China 15 Raymond Ziessel France 15 Jean-Claude G. Bünzli Switzerland 14 Jesús Jiménez-Barbero Spain 14 Detlef Schröder Czech Republic 14 Jan-E. Bäckvall Sweden 13 Osamu Ito Japan 13 Ingo Krossing Germany 13 Tetsuro Majima Japan 13 E. W. Meijer The Netherlands 13 Inside story: In an effort to provide increased visibility for more of our authors we also now feature an inside cover. The articles chosen to appear on the inside cover are highlighted on our news page and in our special cover gallery on the journal homepage. The inside cover for this issue featuring work by Michael Organ et al. is shown below. CH activation has now been added to the list of hot topics on the journal homepage (www.chemeurj.org). The other topics featured on this list currently include organocatalysis, click chemistry, mesoporous materials/metal–organic frameworks, RNA, gold, and sustainable chemistry. Virtual issues are also available on topics such as solar cells, liquid crystals, surfaces and interfaces, magnetic materials, and organic electronics. These lists provide the reader with related content from the family of European Journals, Chemistry—An Asian Journal, Angewandte Chemie, the family of Macromolecular journals, Advanced Materials, Advanced Functional Materials, and Small. Welcome to 2010: The first issue of year features a Review article by Karl-Anker Jørgensen and co-workers1 on organocatalytic asymmetric synthesis of organophosphorus compounds (p. 28) and a fascinating mix of Communications and Full Papers from top authors around the world. 1 The cover highlights work by Gema de la Torre, Dirk M. Guldi, Tomás Torres et al. on lanthanide(III) bis(phthalocyaninato)–C60 dyads (p. 114). The inside cover illustrates research by Chao-Jun Li, Michael Organ and co-workers on the microwave-assisted continuous-flow organic synthesis of propargyl amines (p. 126), and the frontispiece at the beginning of the Full Paper section features work by Kay Severin et al. on cross-reactive sensor arrays for the detection of peptides (p. 104). Papers from members of the Editorial Board also feature prominently in this first issue. Steven V. Ley et al. report on the synthesis of yne–ones by using modular flow reactors (p. 89), C. N. R. Rao describe work on the graphene analogue BCN (p. 149), François Diederich et al. discuss mechanistic work related to the formation of intramolecular charge–transfer chromophores (p. 202), Pekka Pyykkö and his colleague Björn O. Roos investigate the bonding trends in molecular compounds of lanthanides (p. 270), Chi-Ming Che's group together with that of Hartmut Yersin report on phosphorescent platinum(II) Schiff base complexes (p. 233), David Milstein and colleagues discuss the effect of CO on the oxidative addition of arene CH bonds by cationic rhodium complexes (p. 328), Barry M. Trost's group report on catalytic double stereoinduction in asymmetric allylic alkylation of oxindoles (p. 296), and Claudio Toniolo et al. describe the total synthesis of the hexadecapeptide integramide A (p. 316). Thanks: Finally I would like to take this opportunity to thank our dedicated referees and Editorial Board members for all their hard work behind the scenes. Without their help and advice Chemistry—A European Journal would not have succeeded in becoming so successful and growing so successfully over the last 15 years. Together we look forward to providing our readers with even more cutting-edge research from the world of chemistry and its related disciplines in the coming years.1 Neville Compton, Editor

Chemistry-A European Journal has strived to provide a top European forum for top quality Full Papers. Over the years the journal has gone from strength to strength and has continually looked to improve its service to readers and authors by adding new features (Table The growth of the journal has been accompanied by two increases in frequency of publication, as well as by the addition of Concept articles. The success of Chemistry-A European Journal has also paved the way for the launch of several other European publishing projects together with our partnering Chemical Societies (Editorial Union of Chemical Societies (EU ChemSoc)). Over the last 10 years, the European Journal of Organic Chemistry, the European Journal of Inorganic Chemistry, ChemPhysChem, ChemBioChem, and more recently ChemMedChem, have all been successfully launched and become widely accepted and respected by the scientific community. These newer members of the European family offer authors the opportunity to publish research in specialist disciplines in different forms either as Full Papers, Communications, or Review-type articles. The flexibility offered by these journals allows them to offer full coverage of their respective fields, an aspect that is greatly appreciated by readers and authors alike.

Rarely has a concept gained prominence in scientific and everyday discourse as rapidly as sustainability. A decade ago the term was in customary use only among forest rangers, to whom it meant forest management, whereby one should not log more wood than can grow back. The chemical industry has long understood the importance of sustainable management of its resources and the exploration of alternative sources, and academic research has also seized the challenge presented by dwindling fossil fuels and raw materials. In Europe, these efforts are coordinated by the initiative SusChem (sustainable chemistry). “Here is oil! Oil is here! Piston-lubricating oil is here and that which lights the towns”. Thus wrote Bertolt Brecht in a lyric poem three-quarters of a century ago. And today oil remains the resource for energy and materials. Even if one considers that metals play a large role in materials, their extraction and processing require a vast amount of energy. Sustainability in chemistry means the pursuit and utilization of resources other than oil. As an energy source, oil can be substituted by nuclear and solar energy, along with wind, tidal, and hydropower. In particular, the increased use of solar energy, which in many respects would be the most attractive energy source, still requires much research: photocatalysis, photovoltaics, photosynthesis, and the many further forms of “photo” research. The environmentally conscious use of coal must be stepped up; the safe generation, storage, and transport of hydrogen are problems which chemists must work on, not to mention the challenges of carbon dioxide chemistry. Using renewable resources as significant sources of energy and raw materials, but without impairing food production in the process, is a further challenge. And the list can easily be extended! Some solutions to these issues are quickly branded as utopian, but we should not forget what was said of oil 200 years ago at the Russian Academy of Sciences in St. Petersburg: “Oil is a worthless excretion of the Earth—a sticky liquid that stinks and cannot possibly be put to use.”1 It is therefore not surprising that the Gesellschaft Deutscher Chemiker (German Chemical Society, GDCh) made this topic the central theme of the “Science Forum 2007” (Wissenschaftsforum 2007), the biannual conference from September 16 to 19 in Ulm, Germany. The aptly titled conference “Energy, Materials, and Synthesis” will feature plenary lectures on, for example, “Sustainable Energy Supply” (A. Voß) and “New Materials for the Efficient Use of Thermal Energy” (M. Jansen), and there will be symposia on “Chemistry and Materials for Tomorrow's Energy Supply” and “Energy and Material Flow in Civil Engineering”. At the commencement of the conference, the future of chemistry will no doubt also be addressed in the August Wilhelm von Hofmann Lecture, which will be held by George Whitesides on “Rethinking What Chemistry Does”. Incidentally, an eminently readable essay that he wrote on the future of chemistry was published in Angewandte Chemie in 2004: “Assumptions: Taking Chemistry in New Directions”.2 So, we'll see you in Ulm—there are still some places available! The issue in which this editorial appears—in time for the Ulm conference—contains a Review on “Sustainable Concepts in Olefin Metathesis”, which is a title that would not have existed a few years ago. The embodiment of sustainable chemistry is no doubt catalysis in all its varieties: heterogeneous and homogeneous catalysis, bio-, photo-, and electrocatalysis. In the first half of this year, nearly 20 % of the articles in Angewandte Chemie had the word catalysis (in all its variants) in their title! And Issue 38 will be devoted entirely to this topic. On the occasion of the 150th anniversary of the company Süd-Chemie, the beginnings of which go back to none other than Justus von Liebig, Angewandte Chemie is publishing a special thematic issue on catalysis, as catalysts comprise the most important operational division of this venerable enterprise and represent the key to future developments in chemistry. The two Reviews in that issue are titled “Synergies between Bio- and Oil Refineries for the Production of Fuels from Biomass” (A. Corma et al.) and “Liquid-Phase Catalytic Processing of Biomass-Derived Oxygenated Hydrocarbons to Fuels and Chemicals” (J. Dumesic et al.), and they describe research results that could not better represent sustainable chemistry. Both Reviews could well have adorned the first issue of ChemSusChem, which is scheduled to appear at the beginning of 2008. The results of chemical research that are needed for sustainable energy and raw materials for humanity are published in many journals. Angewandte Chemie will naturally continue to concern itself with this theme, as it did, for example, at the beginning of the year with the article “The Future of Energy Supply: Challenges and Opportunities”3 and indeed as it does with many contributions in each issue. But every movement in research has required a vocal medium of its own to strengthen its inherent vitality. ChemSusChem—the name aims to evoke the European platform SusChem (see above)—publishes, as do the sister journals ChemBioChem, ChemMedChem, and ChemPhysChem, both short and long original articles along with reviews of every form and essays on all topics that address chemistry and sustainability with regard to raw materials and energy resources. The first contributions have already been received! The concept “sustainability”, as mentioned above, is used ubiquitously—why then not speak of “sustainable publishing”? ChemSusChem is an excellent case in point: Just as one should not cut down more trees than can grow back, one should also not create more new journals than old ones are discontinued, as no sector can realistically sustain too much of a good thing. This principle could serve as an imperative for sustainable publishing. The Società Chimica Italiana (SCI) will discontinue the journal Annali di Chimica, which was founded in 1911 and more recently published by Wiley-VCH, at the end of this year to make room for ChemSusChem. The founding societies of the new journal will be the SCI and the GDCh, and as its sister journal, ChemSusChem will initially be published in collaboration with Angewandte Chemie. This method guarantees from the start excellent quality and a wide circulation, as all institutional subscribers to Angewandte Chemie will also receive ChemSusChem for at least the first year. The new journal will be operated through the concerted efforts of the editorial staff, an International Advisory Board, and an Editorial Board, the latter of which is headed by Matthias Beller (Rostock, Germany), Gabriele Centi (Messina, Italy), and Daniel G. Nocera (Cambridge, USA). For more information, visit the journal homepage at: www.chemsuschem.org. ChemSusChem is the newest member of the family of European chemistry journals which are published by the Editorial Union of Chemical Societies (EuChemSoc) and with which Chemistry – An Asian Journal, published by the Asian Chemical Editorial Society (ACES), became affiliated last year. 2007 marks the 10th volume of both the European Journal of Inorganic Chemistry and the European Journal of Organic Chemistry, and if one takes a moment to compare how things stood for the predecessor journals in their final year of existence and where the European journals stand today (see Tables 1 and 2), then one can absolutely speak of a sustainable development—especially when one recognizes that from 13 national journals of only regional scope, seven European journals (including ChemSusChem) have been created that are highly regarded the whole world over. The highest Impact Factor for the predecessor journals was 1.8, the lowest among the European journals is now 2.8, and Chemistry – A European Journal has an Impact Factor of over 5! On the basis of such a strong result, great things can be expected from Chemistry – An Asian Journal. After all, 1724 pages were published in the first 12 months in the Asian “Chemistry”, while the European “Chemistry” published “only” just over 1000 pages in the same period 12 years ago. Final year Last IF Pages in last volume Chem. Ber. 1996 1.774 1646 Liebigs Ann. 1996 1.303 2216 Recl. Trav. Chim. Pays-Bas 1996 1.511 548 Bull. Soc. Chim. Fr. 1997 0.786 1082 Bull. Soc. Chim. Belg. 1997 0.473 836 Gazz. Chim. Ital. 1997 0.891 850 An. Quim. 1998 0.312 370 J. Chim. Phys. Phys.-Chim. Biol. 1999 0.45 1634 ACH – Models Chem. 2000 0.571 880 Farmaco 2005 0.79 996 Ann. Chim. 2007 0.516 790[a] IF for 2006 Pages in 2006 Chem. Eur. J. 5.015 9422 Eur. J. Inorg. Chem. 2.704 5164 Eur. J. Org. Chem. 2.769 5602 ChemBioChem 4.100 2054 ChemPhysChem 3.45 2606 ChemMedChem – 1408 When speaking of sustainable publishing, one has to think these days about open access. For over three centuries, scientific publishing has maintained a sustainable circulation of scientific findings and has mastered the many challenges presented by the dramatic increase in the amount of scientific information on the one hand and by an astounding advance in technology on the other. Under a movement which is certainly derived from good intentions but masked behind the illusionary promise of a catchphrase like open access, would things really run more (cost-)efficiently over the long term? Angewandte Chemie itself can certainly look back on a sustainable development: Next year the journal will be 120 years old, and the International Edition will turn 50 in 2011! Under the motto “quality first” Angewandte has improved its performance figures year after year: the number of submitted and published manuscripts, the international scope (Figures 1–1, 2, 3), the Impact Factor and Immediacy Index, online downloads, and the breadth of its scientific scope; today Angewandte Chemie receives articles not only from chemistry institutions and companies, but also from academic and industrial research centers from the biological sciences, engineering sciences, and physics. Thus, a comparison with the top journals of other disciplines is now permissible (Figure 4). Regional distribution of Communications submitted between 1995 and 2007; * denotes extrapolated figures on the basis of the first six calendar months. Distribution of Communications submitted from Western Europe between 1995 and 2007; * denotes extrapolated figures on the basis of the first six calendar months. Distribution of Communications submitted from South and East Asia between 1995 and 2007; * denotes extrapolated figures on the basis of the first six calendar months. Trends in the Impact Factor from 2002 to 2006; source: Institute of Scientific Information, Philadelphia, USA. The recent increase in Angewandte Chemie's Impact Factor to over 10 is not making life any easier for the editorial staff: The number of submitted manuscripts will continue to climb. In July 2007, we received, for the first time ever, more than 500 Communications within one calendar month (not to mention Reviews, Highlights, Book Reviews, etc.), which means that in spite of the growth in the number of articles published, even more articles will have to be rejected. Thus, we must ask our referees to take a more critical approach to their evaluations, and we ask our authors to be more self-critical and to be even more understanding that we cannot possibly accept all manuscripts submitted to us—to be realistic only about 25 %! This for all intents and purposes positive development of Angewandte Chemie has only been possible thanks to the tireless efforts of our dedicated editorial staff,4 thanks to the sound assistance of our distinguished Editorial Board and esteemed International Advisory Board, as well as thanks to the help of innumerable referees from all over the world. Of the more than 4000 referees for the year 2006, several reviewed more than 20 manuscripts! After serving nearly 25 years as Editor-in-Chief, I would like to thank the many faithful readers and authors. I and the rest of the entire editorial staff are indebted to your constructive criticism and loyalty. Peter Gölitz PS: Starting in 2008, Angewandte Chemie will be publishing 52 instead of 48 issues per year. Is this difference, in a time of online publishing and daily posting of articles in Early View mode, not more or less trivial? Quite the contrary! In the Early View mode, only the individual articles are recognized, but in an issue, readers are treated to a comprehensive presentation that offers additional incentive to read contributions from outside their own field—an element which for a journal that presents chemistry in all its many facets is indispensable.