NosocomialBurkholderia cepaciaInfection and Colonization Associated With Intrinsically Contaminated Mouthwash—Arizona, 1998

doi:10.1001/jama.281.4.318-jwr0127-4-1

Abstract

During August 1996-June 1998, 74 patients at two hospitals in Arizona had cultures positive for Burkholderia cepacia. Most isolates were from the respiratory tracts of patients in intensive-care units (ICUs). Because of the large number of B. cepacia isolates, personnel at both hospitals requested the Arizona Department of Health Services assist in an investigation. This report summarizes the results of the investigation.

Highlights

DURING AUGUST 10-NOVEMBER 23, 1998, 33 confirmed* measles cases were reported to the Anchorage Department of Health and Human Services and the Alaska Department of Health and Social Services (ADHSS)
Antibody test, and seven met the clinical case definition. This was the largest outbreak of measles in the United States since 1996.1,2 This report summarizes results of the epidemiologic investigation conducted by ADHSS and underscores the importance of second-dose requirements for measles vaccine
The child was hospitalized for 1 day, and measles was diagnosed by positive rubeola IgM enzyme-linked immunosorbent assay

Summary

Transmission of Measles Among a Highly Vaccinated

26 cases were confirmed by positive rubeola IgM antibody test, and seven met the clinical case definition This was the largest outbreak of measles in the United States since 1996.1,2 This report summarizes results of the epidemiologic investigation conducted by ADHSS and underscores the importance of second-dose requirements for measles vaccine. On September 5, 26 days after onset of the imported case, a 16-yearold high school student developed measles, confirmed by IgM testing. 15 other students and one teacher at the same high school developed measles during September 14October 4; 12 cases were laboratory confirmed. CDC Editorial Note: The occurrence of this outbreak primarily in one school, despite the extremely high one-dose measles vaccine coverage, demonstrates the importance of school requirements for a second dose of MCV. Most children respond to a second dose, and .99% of persons aged $12 months receiving two or more doses at least 28 days apart develop immunity

The Advisory Committee on Immunization Practices and the American

Preemptive State

Findings

Associated With