Abstract
Nosocomial Drug-Resistant Bacteremia in 2 Cohorts with Cryptococcal Meningitis, Africa
Highlights
Limited data are available for sub-Saharan Africa regarding multidrug-resistant infections [1,2]
We reviewed bacteremia episodes in cryptococcal meningitis cohorts in Kampala, Uganda (n = 115 episodes) and Cape Town, South Africa (n = 72) during November 2010–April 2013
Data were obtained from the prospective cryptococcal optimal antiretroviral therapy timing trial, a randomized strategy trial assessing optimal antiretroviral therapy timing (n = 142) and another prospective observational cohort in Cape Town (n = 45)
Summary
Limited data are available for sub-Saharan Africa regarding multidrug-resistant infections [1,2]. We reviewed bacteremia episodes in cryptococcal meningitis cohorts in Kampala, Uganda (n = 115 episodes) and Cape Town, South Africa (n = 72) during November 2010–April 2013. Data were obtained from the prospective cryptococcal optimal antiretroviral therapy timing trial We enrolled HIV-infected adults who had a first episode of cryptococcal meningitis diagnosed by cerebrospinal fluid culture or cryptococcal antigen testing.
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