Abstract
Recent transmission of dengue viruses has increased in tropical and subtropical areas and in industrialized countries because of international travel. We describe a case of nosocomial transmission of dengue virus in Germany by a needlestick injury. Diagnosis was made by TaqMan reverse transcription–polymerase chain reaction when serologic studies were negative.
Highlights
Recent transmission of dengue viruses has increased in tropical and subtropical areas and in industrialized countries because of international travel
On day 2n, she visited our service, where dengue virus infection was diagnosed by using a Light Cycler (Roche Diagnostics, Mannheim, Germany) polymerase chain reaction (PCR) method
Serologic studies were performed with the PanBio dengue immunoglobulin (Ig) M capture enzyme-linked immunosorbent assay (ELISA) and PanBio dengue indirect IgG ELISA (PanBio Ltd., Brisbane, Australia) [3]; arbitrary units relative to a simultaneously measured calibrator >11 were considered positive
Summary
Recent transmission of dengue viruses has increased in tropical and subtropical areas and in industrialized countries because of international travel. We describe a case of nosocomial transmission of dengue virus in Germany by a needlestick injury. On day 2n, she visited our service, where dengue virus infection was diagnosed by using a Light Cycler (Roche Diagnostics, Mannheim, Germany) polymerase chain reaction (PCR) method. Her symptoms lessened gradually over the course of 4 weeks, and she was on sick leave for 5 weeks. Dengue virus infection was subsequently diagnosed, and mild hepatitis and a rash developed. She was discharged in good condition after the fever subsided. Immunoglobulin; PCR, polymerase chain reaction; n.d., not done
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