Abstract
To the Editor:— Naphazoline (Privine) hydrochloride, tetrahydrozoline hydrochloride (Tyzine), oxymetazoline hydrochloride (Afrin), and xylometazoline (Otrivin) hydrochloride are potent vasoconstrictors used to relieve nasal stuffiness. The other major effect of these drugs is depression of the central nervous system. Several years ago,LETTERS TO THE EDITORinThe Journalreminded physicians of possible harmful side effects of this class of drugs in infants and small children. 1,2 A recent experience with xylometazoline nose drops demonstrates the importance of keeping this warning in mind. Report of a Case:— A 1-month-old Negro male infant was seen in the pediatric clinic at Martin Army Hospital, Ft. Benning, Ga. The patient exhibited poor responsiveness and gasping respirations. He was rushed to the ward with the initial impression of meningitis, encephalitis, or severe pneumonia. Physical examination, laboratory studies including salicylate level and spinal fluid examination, and chest x-ray film failed to reveal any specific abnormality. The
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