Abstract
Objective:To screen the Chinese herbal medicine with anti-pulmonary fibrosis, to provide reference for further study on anti-drug pulmonary fibrosis. Methods By complement lysis test, oleinic acid model of rats and paraquat model of mice were made as pulmonary fibrosis animal model to screen the medicine activity. Results in vitro, Cangzhu and Tinglizi had great significance in inhibition of RBC hemolysis; in vivo, compared with Control group, Hyp content of lung tissues in animal model groups had statistical significance; compared with model group, Hyp content of therapy groups had statistical significance, pathological lesion was reduced. Conclusion Extracts of Cangzhu and Tinglizi has certain resistance to pulmonary fibrosis activity.
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