Normative Structure of Resting-State EEG in Bipolar Derivations for Daily Clinical Practice: A Pilot Study.

Abstract

We used numerical methods to define the normative structure of resting-state EEG (rsEEG) in a pilot study of 37 healthy subjects (10-74 years old), using a double-banana bipolar montage. Artifact-free 120-200 s epoch lengths were visually identified and divided into 1 s windows with a 10% overlap. Differential channels were grouped by frontal, parieto-occipital, and temporal lobes. For every channel, the power spectrum was calculated and used to compute the area for delta (0-4 Hz), theta (4-8 Hz), alpha (8-13 Hz), and beta (13-30 Hz) bands and was log-transformed. Furthermore, Shannon's spectral entropy (SSE) and coherence by bands were computed. Finally, we also calculated the main frequency and amplitude of the posterior dominant rhythm. According to the age-dependent distribution of the bands, we divided the patients in the following three groups: younger than 20; between 21 and 50; and older than 51 years old. The distribution of bands and coherence was different for the three groups depending on the brain lobes. We described the normative equations for the three age groups and for every brain lobe. We showed the feasibility of a normative structure of rsEEG picked up with a double-banana montage.