Abstract

Numerous normal age-related changes that occur in the nervous system differ more quantitatively than qualitatively from certain common neurological diseases of elder individuals. Changes in the cranial nerve examination primarily relate to an age-related decline in sensory functions, especially of vision and hearing, and to a restriction in the range of eye movements, especially vertically. A progressive decline in the bulk and strength of muscles and in the speed and coordination of movements has long been recognised as an accompaniment of aging. Posture and gait show conspicuous changes with advancing age, partially correlating with diminished sensation in the legs and/or with a nonspecific bradykinetic senile gait. The distal depression of deep tendon reflexes and sensory function is primarily due to distal degeneration of sensory axons. Among the release signs, only the reappearance of the grasp reflex is a reliable sign for indicating pathology of the nervous system. Senile tremor, a decline in the maintenance of thermal homoeostasis, an increasing frequency of orthostatic hypotension, and disorders of sleep are also commonly associated with aging.

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