Abstract
Hemorrhagic shock (HS) and traumatic brain injury (TBI) are the leading causes of trauma related deaths. These insults disrupt both the coagulation system and the normal neuroprotective endothelial functions. We have previously reported that resuscitation with 0.9% normal saline (NS) results in increased brain lesion size and swelling compared with fresh frozen plasma (FFP) and colloids (Hextend, HEX) in a swine model of TBI+HS. The goal of this study was to determine whether those findings were associated with differential effects of these fluids on the coagulation and endothelial systems.
Sign-in/Register to access full text options 
Talk to us
Join us for a 30 min session where you can share your feedback and ask us any queries you have
Schedule a callDisclaimer: All third-party content on this website/platform is and will remain the property of their respective owners and is provided on "as is" basis without any warranties, express or implied. Use of third-party content does not indicate any affiliation, sponsorship with or endorsement by them. Any references to third-party content is to identify the corresponding services and shall be considered fair use under The CopyrightLaw.
