Abstract
Cerebrospinal fluid (CSF) dynamics and intracranial pressure-volume relationships can be studied by a wide variety of procedures in clinical settings. Although infusion methods are considered to give better estimates of the resistance to outflow of the CSF (Rout), the technique described by Marmarou et al. [4] is attractive because it is relatively simple, fast and reliable. By the bolus test, we can, by a single procedure, calculate the pressure volume index (PVI), Rout and the compliance of the craniospinal axis (Ccsf). Nevertheless, the value of this procedure in studying patients with suspected abnormal CSF hydrodynamics and especially in selecting patients for shunting in so-called “Normal pressure hydrocephalus” has been rather controversial. One of the problems when trying to define normal CSF dynamics is the lack of normal control values. The present study was undertaken to determine normal PVI, Rout and Ccsf in adults without intracranial pathology.
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