Abstract
Conclusions(1) From the data presented the normal range of prothrombin-clotting time has been observed to be from 25 to 30 sec. Values above 30 sec have given a whole blood index of 1.0 plus. These results yield closer correlation to other methods for estimating the prothrombin level. (2) Treated and untreated patients with pernicious anemia, pellagra and other pathologic conditions have similar normal prothrombin values. Treated sprue patients gave similar results. In a case of sprue (relapsing) with persistent diarrhea, the prothrombin level was found to be almost normal. (3) When abnormal variations occur in wet or dry readings, it may be more accurate to depend upon the whole blood clotting index.
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