Abstract

IntroductionTemporomandibular disorders (TMD) are observed in a number of autoimmune diseases but limited studies have assessed the effect of autoimmune diseases on TMD. Therefore, the present review article was conducted to determine the effect of autoimmune diseases on TMD.MethodsInternational databases, including Web of Sciences, PubMed and Scopus, were searched in order to find related articles. The search key words were; temporomandibular joint (TMJ) autoimmune disorders, TMJ, TMD, medical therapy and non-invasive, local and systemic management. Published articles from June, 2010 to June, 2019 were included in the review.ResultsA total of 11 related articles including rheumatoid arthritis (RA), lupus erythematosus and systemic sclerosis were found. All articles noted that TMJ has unique features that distinguishes it from other human body joints. Cases of TMJ injury and TMD require specific treatments. Therefore, early diagnosis of TMD is essential. It was also mentioned in the articles that the collagen-induced arthritis (CIA) method is a suitable method for investigating TMD and its relationship with RA. Treatment methods included oral steroids, Disease-modifying antirheumatic drugs, nonsteroidal anti-inflammatory drugs, methotrexate 75 mg, and combination therapy with methotrexate.ConclusionBased on the results of this study, TMD exists in some autoimmune diseases, including RA, lupus erythematosus and systemic sclerosis. Therefore, there should be an interdisciplinary collaboration between physicians and dentists in order to choose the best conservative treatment and medication therapy for TMD to reduce the progression and pain associated with this type of disorder.

Highlights

  • Temporomandibular disorders (TMD) are observed in a number of autoimmune diseases but limited studies have assessed the effect of autoimmune diseases on temporomandibular diseases (TMDs)

  • Based on the results of this study, TMD exists in some autoimmune diseases, including rheumatoid arthritis (RA), lupus erythematosus and systemic sclerosis

  • A total of 78 articles were found in the literature search, among which 11 articles were found to be related to the effect of autoimmune diseases on TMD

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Summary

Introduction

Temporomandibular disorders (TMD) are observed in a number of autoimmune diseases but limited studies have assessed the effect of autoimmune diseases on TMD. The present review article was conducted to determine the effect of autoimmune diseases on TMD. The search key words were; temporomandibular joint (TMJ) autoimmune disorders, TMJ, TMD, medical therapy and non-invasive, local and systemic management. Conclusion: Based on the results of this study, TMD exists in some autoimmune diseases, including RA, lupus erythematosus and systemic sclerosis. Due to limited knowledge regarding the anatomy, function, and physiological changes of TMJ, numerous diagnostic errors have been observed for temporomandibular diseases (TMDs) [3]. TMD is observed in a variety of autoimmune diseases, including rheumatism and osteoarthritis. Limited studies have been performed to assess the effects of autoimmune diseases on TMD. Based on the above-mentioned and limited specialized studies about the effects of autoimmune diseases on TMD, this review study was performed in order to determine the effect of autoimmune diseases in TMD

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