Nonstent intervention treatment of airway stenosis after tuberculosis

Abstract

Objective With the increase of floating population and acquired immune deficiency syndrome (AIDS) patients, tuberculosis patients are gradually increasing.6.4%-40% active tuberculosis patients will appear bronchial tuberculosis, and more than 90% of endobronchial tuberculosis patients will appear different degree of airway stenosis.There are advantages and disadvantages of the previous treatment methods of surgery and stent implantation, which is not suitable for all patients.We used the nonstent intervention treatment method (balloon dilation + cryotherapy + needle electric knife + local drug) for the treatment of airway stenosis after tuberculosis, and have obtained satisfactory curative effects.The efficacy and safety of nonstent intervention treatment method in the treatment of airway stenosis after tuberculosis were studied in this paper. Methods This study included 24 patients with airway stenosis after tuberculosis in the Department of Respiration Medicine, Beijing Tiantan Hospital, Capital Medical University, from January 2012 to April 2014.According to the type of the lesion, the patients were divided into 2 groups, 3 people in the web-like stenosis group, 21 in the complex stenosis group.After balloon dilatation, cryotherapy and / or high frequency electric knife, we locally used Mitomycin (MMC) or Paclitaxel by self-made catheter in the lesion.The main evaluation indexes were the curative effect, the improvement rate of airway stenosis and dyspnea index, and the incidence of complications were also observed. Results According to our clinical curative effect criteria, 16 cases were cured, 6 cases were effective, 0 cases were ineffective, 2 cases were failure, the cure rate was 66.7%, the effective rate was 91.7%.There were no statistically significant differences in the therapeutic efficacy of different types of airway stenosis (P=0.833), and no serious complications were observed. Conclusions In the treatment of airway stenosis after tuberculosis, nonstent intervention therapy can achieve good therapeutic effects and safety, and is worth popularizing in clinical medicine. Key words: Tuberculosis; Airway stenosis; Bronchoscopy; Intervention therapy; Curative effect