Abstract

BackgroundAlthough the nonprescribed use of tranquilizers or sedatives by adolescents is a cause for concern in many countries, there is a shortage of data from low and middle income countries (LAMIC). The present study aims to estimate the prevalence of nonprescribed use of tranquilizers/sedatives by adolescents in Brazil, and to assess how socioeconomic and demographic circumstances, as well as indicators of access to these substances are associated with their use and with risk perception.MethodsA cross-sectional study was conducted using a multi-stage probability sample of 18131 high school students from public and private schools from all 27 Brazilian state capitals. A self-reporting questionnaire was used to obtain information on social and economic circumstances, nonprescribed use of tranquilizers or sedatives and risk perception of their use.ResultsLifetime nonprescribed use of tranquilizers or sedatives was reported by 5% of respondents, more commonly among females (OR: 2.19, 95% CI: 1.75-2.75) and those attending private schools (OR: 1.47, 95% CI: 1.17-1.84). The use of tranquilizers/sedatives by relatives or friends was associated with nonprescribed use by the participant (OR: 4.26, 95% CI: 3.46-5.23) and a majority of lifetime users obtained these substances from a family environment (82%). Previous medical prescription was independently associated with nonprescribed use (OR: 6.61, 95% CI: 4.87-8.98) and with low risk perception (OR: 2.42, 95% CI: 1.12-5.24).ConclusionsA substantial proportion of Brazilian adolescents use nonprescribed tranquilizers/sedatives. Easy access to these substances seems to play an important role in this use and should be tackled by preventive and treatment interventions.

Highlights

  • The nonprescribed use of tranquilizers or sedatives by adolescents is a cause for concern in many countries, there is a shortage of data from low and middle income countries (LAMIC)

  • Lifetime nonprescribed use of tranquilizers or sedatives was reported by 5.0% of respondents (n = 1076)

  • One in 10 participants reported the use of tranquilizers or sedatives by a family member or a friend, 2.6% had received a prescription for these substances in the past and 7.2% perceived their regular use as low risk

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Summary

Introduction

The nonprescribed use of tranquilizers or sedatives by adolescents is a cause for concern in many countries, there is a shortage of data from low and middle income countries (LAMIC). A survey in the USA showed that 6.5% of students had used nonprescribed tranquilizers [2] whilst a study in 31 European countries showed an average prevalence of 5.6% of those who had ever used tranquilizer/sedatives with considerable variation between countries (from around 1.5% in Ukraine and the United Kingdom to about 13% in Lithuania and France) [3]. These substances may be seen as being “safer” than illicit drugs since they are produced by pharmaceutical companies, prescribed by physicians and widely consumed by millions of people [4,5]. It is important to have some better idea about their use among adolescents

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