Abstract
In Taiwan, lower nonpolio enterovirus activity during the coronavirus disease pandemic in 2020 compared with 2014–2019 might be attributable to adherence to nonpharmaceutical interventions. The preventable fraction among unexposed persons indicated that 90% of nonpolio enterovirus activity might have been prevented during 2014–2019 by adopting the same measures enforced in 2020.
Highlights
In Taiwan, lower nonpolio enterovirus activity during the coronavirus disease pandemic in 2020 compared with 2014–2019 might be attributable to adherence to nonpharmaceutical interventions
We estimated the change in nonpolio enteroviruses (NPEV) activity after the first imported COVID-19 case in Taiwan, when nonpharmaceutical interventions were introduced and enforced, by using a differencein-difference model used in a previous influenza study (Appendix) (4)
We estimated the preventable fraction among the unexposed (PFu) to measure the reduction of NPEV that would have been possible in each week of the 2014–2019 seasons, had the same nonpharmaceutical interventions been strictly followed, and adjusted PFu to control for potential confounder (Appendix)
Summary
In Taiwan, lower nonpolio enterovirus activity during the coronavirus disease pandemic in 2020 compared with 2014–2019 might be attributable to adherence to nonpharmaceutical interventions. We collected nationwide data on weekly outpatient and emergency department (ED) visits during November 2014–June 2020 from the Taiwan National Infectious Disease Statistics System We estimated the change in NPEV activity after the first imported COVID-19 case in Taiwan, when nonpharmaceutical interventions were introduced and enforced, by using a differencein-difference model used in a previous influenza study (Appendix) (4).
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