Abstract

International travel–related nonpharmaceutical interventions (NPIs), which can include traveler screening, travel restrictions, and border closures, often are included in national influenza pandemic preparedness plans. We performed systematic reviews to identify evidence for their effectiveness. We found 15 studies in total. Some studies reported that NPIs could delay the introduction of influenza virus. However, no available evidence indicated that screening of inbound travelers would have a substantial effect on preventing spread of pandemic influenza, and no studies examining exit screening were found. Some studies reported that travel restrictions could delay the start of local transmission and slow international spread, and 1 study indicated that small Pacific islands were able to prevent importation of pandemic influenza during 1918–19 through complete border closure. This limited evidence base indicates that international travel-related NPIs would have limited effectiveness in controlling pandemic influenza and that these measures require considerable resources to implement.

Highlights

  • International travel–related nonpharmaceutical interventions (NPIs), which can include traveler screening, travel restrictions, and border closures, often are included in national influenza pandemic preparedness plans

  • We aimed to review the evidence base assessing the effectiveness of these travel-related NPIs against pandemic influenza and to identify the barriers to implementation of these interventions

  • We searched for literature reporting or estimating the effectiveness of NPIs related to international travel and movement, including entry and exit screening travelers, travel restrictions, and border closures on pandemic or interpandemic influenza

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Summary

POLICY REVIEW

No available evidence indicated that screening of inbound travelers would have a substantial effect on preventing spread of pandemic influenza, and no studies examining exit screening were found. Some studies reported that travel restrictions could delay the start of local transmission and slow international spread, and 1 study indicated that small Pacific islands were able to prevent importation of pandemic influenza during 1918–19 through complete border closure. This limited evidence base indicates that international travelrelated NPIs would have limited effectiveness in controlling pandemic influenza and that these measures require considerable resources to implement. We aimed to review the evidence base assessing the effectiveness of these travel-related NPIs against pandemic influenza and to identify the barriers to implementation of these interventions

Methods and Results
International travel restriction
Border closure
Travel restriction
Discussion
Full Text
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