Non-oxygenation factors relate with postoperative prolonged mechanical ventilation in aortic dissection patients

Abstract

Objective To identify the correlative and risk factors of non-oxygenation factors associated with postoperative prolonged mechanical ventilation (PMV) of aortic dissection(AD). Methods AD patients undergoing surgery during January 2010 and January 2015 were enrolled. Prolonged mechanical ventilation was defined that duration of ventilation more than 48 h. Results There were 240 patients, average age was (50±12)years. The correlative factors with postoperative PMV were: pre-opervative white blood cell (WBC) (r=0.241, P=0.003), emergency operation (r=0.263, P=0.004), Debakey type(r=-0.379, P=0.000), duration of operation(r=0.329, P=0.000), postoperative diastolic pressure(r=-0.205, P=0.007), heart rate(r=0.246, P=0.001), postoperative hemoglobin (r=-0.213, P=0.005), calcium(r=-0.262, P=0.001), glucose (r=0.274, P=0.000), lactate(r=0.272, P=0.000)and pericardial effusion(r=0.239, P=0.032). Logistic analysis indicated that: the duration of operation, WBC and postoperative blood calcium were: 2.063, 1.285, 0.016, respectivly(all P<0.05). Conclusions The correlative factors were: preoperative WBC, emergency operation, Debakey Type, duration of operation, heart rate, postoperative diastolic pressure, hemoglobin, calcium, glucose, lactate, and pericardial effusion. Duration of operation, WBC and postoperative blood calcium were risk factors predicting PMV. Key words: Aortic diseases; Airway management; Risk factors