Abstract
Nonmotor symptoms of Parkinson disease significantly hamper the quality of life of patients and have prognostic significance. To evaluate the presence of nonmotor symptoms in patients with Parkinson disease. A structured interview was carried out in 32 patients aged 74 ± 9 years (53% men) with Parkinson disease asking specifically for impulse control disorders and dopaminergic dysregulation. The following scales were also applied: Hoehn & Yahr scale, Montreal Cognitive Assessment, Geriatric depression scale, Nonmotor symptom scale and REM sleep scale. A high frequency of nonmotor symptoms was recorded, specially mood, sleep, urinary and gastrointestinal problems and impulse control disorders. Nonmotor symptoms must be actively sought and managed in patients with Parkinson disease.
Highlights
Nonmotor symptoms of Parkinson disease significantly hamper the quality of life of patients
with Parkinson disease asking for impulse control disorders
et al The metric properties of a novel non-motor symptoms scale for Parkinson's disease
Summary
Nonmotor symptoms of Parkinson disease significantly hamper the quality of life of patients and have prognostic significance. Los SNM determinan un impacto incluso mayor que los síntomas motores sobre la calidad de vida en pacientes con EP8. Así como existen subtipos motores de la EP (predominio temblor, inestabilidad postural/alteración de la marcha, o mixtos)[9], algunos autores han propuesto relacionar los grupos de dominios de SNM afectados con probables biomarcadores, estableciendo los subtipos de “tronco, límbico y cortical”[10]. Los trastornos del descontrol de impulsos son definidos como conductas repetitivas, excesivas y compulsivas, en un nivel que interfiere con el normal funcionamiento de una persona. Los trastornos del control de impulso han sido reportados en 20% de pacientes con EP sin tratamiento, sin embargo está fuertemente asociado con el uso de agonistas dopaminérgicos, de manera dosis dependiente, llegando a una prevalencia de más de 50% en algunos trabajos[13]. Con el fin de identificar las principales manifestaciones no motoras de los pacientes con EP del CESFAM no 5 e intentar establecer estrategias efectivas y complementarias en la evaluación y monitorización de estos síntomas, se llevo a cabo el presente trabajo
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