Abstract
In this work, a recursive nonlinear feedback control law for the regulation of the outlet substrate concentration for a fixed bed bioreactor with immobilized biomass is designed. The control algorithm is based on a reduced order model related with ordinary differential equations and only made use of a discrete substrate outlet concentration for its implementation. It is shown that the proposed control algorithm is robust against disturbances in the input substrate concentration. The performance of the proposed regulation scheme is illustrated by means of numerical simulations. © 1999 Society of Chemical Industry
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