Abstract
Vibrational microscopy based on the mid-infrared (MIR) absorption of molecular modes is a proven strategy for label-free imaging. Yet, as a tool for cellular imaging, MIR vibrational imaging suffers from several shortcomings., among which the low spatial resolution and the unavailability of affordable imaging cameras with high pixel densities. In this presentation, we will discuss how nonlinear optical (NLO) interactions can be employed to improve MIR imaging considerably. First, we introduce a new NLO method for capturing MIR images on a regular Si-based camera. Second, we highlight how NLO interactions can be used to improve the resolution in MIR microscopy.
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