Abstract
Abstract Although toluene diisocyanate (TDI) has been widely used for about 50 years, industrial hygiene characterizations of other chemical exposures used in conjunction with TDI have generally received much less attention. As part of a retrospective, cohort mortality study, industrial hygiene evaluations were performed in three facilities manufacturing flexible (TDI-based) foam. This report is concerned only with nonisocyanate exposures in that industry. In each facility, the concentrations of several air contaminants, other than TDI, were assessed, including aliphatic amines, nitrosamines, nitrogen dioxide, thermal degradation products, organic solvents, polyurethane dust, and flame retardants. Air samples were also collected for subsequent assay of mutagenic activity using Salmonella bacterial tester strains TA98 and TA100. Workers were found to have respiratory and probably dermal exposure to methylene chloride in each facility. Traces of nitrogen dioxide and some aliphatic amines were evident. Howev...
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