Non-Iron Model Studies on Dioxygenases

Abstract

Catalytic dioxygenation reactions by non-native metal complexes are important for understanding dioxygenase reactions on the basis of coordination chemistry. The incorporation of dioxygen into the benzene ring resulting in the oxidative ring opening is well known as the intradiol and extradiol dioxygenase reactions, where iron centers play an important role [1] Tsuji et al. [2-5] have reported that catechol undergoes oxidative cleavage of the aromatic ring by oxygenation catalyzed with CuCl in pyridine containing a small amount of methanol to give cis, cis-muconic acid monomethyl ester in good yield [eq. (1)] and they proposed a mechanism involving the incorporation of dioxygen activated by the Cu complex.KeywordsCyclic VoltammogramSchiff BaseTernary ComplexSchiff Base LigandIonic DissociationThese keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.