Abstract

Key pointsWhat is already known? Placentas of dichorionic twins are fused in approximately 40% of the cases, and blood chimeras can originate upon transfer of cells. In general, dizygotic twins always have a dichorionic placenta, but as an exception, monochorionic dizygotic twins exist, which can lead to blood chimerism. What does this study add? Blood chimerism due to either a monochorionic placenta in fraternal twins or transfer of cells between fused placentas can adopt a permanent state. Blood chimerism in sex‐discordant twins can lead to aberrant patterns in the non‐invasive prenatal test of adult female twins.

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