Noninvasive identification of directionally-dependent elastic properties of soft tissues using full-field optical data

Abstract

This paper introduces an innovative approach for elastic property characterization of soft tissues, having directional-dependent material behavior, via their vibration response measurement and interpretation. The full-field time-dependent surface displacements as a result of externally excited soft tissues are collected through digital image correlation (DIC). A developed analytical model, capturing the low-amplitude vibration behavior of anisotropic layered human skin with the incorporation of the influence of subcutaneous elasticity and inertia, is employed to accurately predict its resonant frequencies and pertaining displacement field images. An efficient solution approach for the model is implemented into an inverse algorithm to rapidly characterize the anisotropic elastic properties based on importing the vibration characteristics. To show the merit of the approach, a 3-D finite element (FE) simulation model was used to generate full-field data, detected and matched with a set of specific vibration modes via modal assurance criterion (MAC). The validity of the model implemented into the inverse characterization algorithm is demonstrated through a comparison of predicted vibration frequencies and mode-shapes simulated via the 3-D FE model for different cases with anisotropic elastic properties in different layers of the skin. It is shown that modes are influenced differently when anisotropic properties are introduced to the model. Thus, the established inverse characterization algorithm is capable of rapidly predicting the elastic material properties of anisotropic soft sheets with adequate accuracy.