Abstract
Purpose. The aim of our study was to non-invasively investigate the parameters of coronary blood flow during exercise in patients with arterial hypertension. Materials and Methods. We enrolled 144 patients with arterial hypertension. All patients performed supine bicycle symptoms-limited tests. Throughout the exercise, the diastolic peaks of coronary flow velocity in left anterior descending artery (LAD) were measured. The values of diastolic velocity before and at maximal exercise, coronary flow velocity reserve (CFVR) and difference between peak and rest velocities were calculated offline. The control group consisted of 145 healthy persons. Results. The rest blood flow velocity in LAD was 33.0±8.4 cm/s, the peak velocity in LAD was 80.3±16.5 cm/s, difference of velocities was 48.2±13.9 cm/s, CFVR was 2.55±0.56. Women and men were comparable in velocity parameters during exercise test. There was no significant correlation between mass/index of left ventricle mass and velocity data in LAD. Hypertensive patients were comparable in investigated coronary artery flow parameters with healthy group. Conclusions. During supine bicycle tests, the patients with arterial hypertension have a similar coronary artery flow velocity profile with healthy persons.
Highlights
The control group consisted of 145 healthy persons
There was no significant correlation between mass/index of left ventricle mass and velocity data in left anterior descending artery (LAD)
Hypertensive patients were comparable in investigated coronary artery flow parameters with healthy group
Summary
В покое у пациентов с артериальной гипертензией скорость коронарного кровотока в срединном сегменте ПМЖВ была 33,0 ± 8,4 см/с, скорость на пике нагрузки – 80,3 ± 16,5 см/с, разница скорости на пике и до нагрузки – 48,2 ± 13,9 см/с, значение КРпмжв – 2,55 ± 0,56. Пациенты с артериальной гипертензией имеют скоростные значения коронарного кровотока во время теста с физической нагрузкой, не отличающиеся от параметров группы здоровых лиц. Цель исследования — неинвазивное измерение скоростных параметров коронарного кровотока у лиц с артериальной гипертензией, изучение влияния возраста и пола на данные показатели, сравнение исследуемых параметров с аналогичными у здоровых людей. Материал и методы исследования Из базы пациентов между ноябрем 2011 года и декабрем 2014 года были проанализированы данные всех лиц, прошедших стресс-эхокардиографическое исследование с визуализацией передней межжелудочковой артерии до и на пике нагрузки — всего 3237 человек.
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