Abstract
The capacity of nonpolio enteroviruses to cause paralytic central nervous system disease has become increasingly apparent. With the suppression of poliovirus infection by mass immunization, the nonpolioviruses account for an increasing proportion of significant paralytic disease. An ECHO 4 virus was isolated from the spinal fluid of a 28-month-old child with severe bulbospinal paralysis. Clinical findings, indistinguishable from those of acute bulbospinal poliomyelitis, are described. The status of ECHO virus infection as a cause of significant paralytic disease is reviewed.
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