Abstract
Molecularly imprinted polymer (MIP) receptors have been synthesized, characterized, and applied as new selective receptors in solid-contact ion selective electrodes (ISEs) towards non-dissociated 3,5-dihydroxytoluene (orcinol). Two monomers, namely methacrylic acid (MAA) and acrylamide (AA), were used in the preparation of MIP receptors. Graphene (Gr) was used as the solid contact material between the sensing membrane and the electrical contact substrate. Based on non-equilibrium sensing mechanism, the proposed sensors reveal observably enhanced detection sensitivity towards orcinol with detection limits 1.7 × 10−5 and 3.3 × 10−6 M for sensors based on MIP/MAA and MIP/AA, respectively. The selectivity coefficients measured by the modified separate solution method (MSSM) for the proposed sensors showed good selectivity towards orcinol over most common other phenols and inorganic anions. All measurements were made in the presence of 30 mM phosphate buffer solution (PBS) with a pH of 7.0. Potential stability for the proposed sensors was tested by constant-current chronopotentiometry. No water films were formed between the sensing membrane and the electron conductor substrate. The applicability of MIP/MAA incorporated ISE has been checked by recovery test of orcinol in the presence of soil matrix and by standard addition method.
Highlights
In recent years, potentiometric sensors, or so-called “polymeric membrane ion-selective electrodes (ISEs)”, have become an attractive tool for determination of ionic species in different fields, such as clinical diagnostics and trace-level environmental assessment [1,2,3,4,5]
Integration of molecularly imprinted polymers (MIPs) with potentiometric sensors is exhibiting a great potential to significantly change the view of using non-affordable ionophores, which are characterized by their high cost, or using ion exchangers, which are characterized by their poor selectivity
Potentiometric sensors based on different MIP receptors have been synthesized for determination of different organic species in either their ionic or neutral forms [14,15,16]
Summary
Potentiometric sensors, or so-called “polymeric membrane ion-selective electrodes (ISEs)”, have become an attractive tool for determination of ionic species in different fields, such as clinical diagnostics and trace-level environmental assessment [1,2,3,4,5]. This can be attributed to their intrinsic advantages, such as high selectivity, ease of use, and good reliability. In spite of their success in the determination of organic species, almost all of these previously reported ISEs integrated with MIPs are in classical liquid-contact mode
Sign-in/Register to view highlights & summary Talk to us
Join us for a 30 min session where you can share your feedback and ask us any queries you have
Schedule a callDisclaimer: All third-party content on this website/platform is and will remain the property of their respective owners and is provided on "as is" basis without any warranties, express or implied. Use of third-party content does not indicate any affiliation, sponsorship with or endorsement by them. Any references to third-party content is to identify the corresponding services and shall be considered fair use under The CopyrightLaw.
