Nonequilibrium Model for Yeast Cell Cycle

Abstract

In the living cells, molecules including proteins, DNAs, RNAs and so on, with interactions between them cooperate as networks that govern various cellular functions. In this paper, a stochastic model with trigger mechanism is proposed based on what are known about the genes and proteins controlling the cell cycle of budding yeast. With respect to the biological observations, it looks more natural and understandable than deterministic dynamical model and our former stochastic model. Our model vividly describes that the protein interaction network goes through the biological pathway and forms an endless loop.