Non-contrast MR portography using time-spatial labeling inversion pulse for diagnosis of portal vein pathology

Mahmoud Abd Elaziz Dawoud,Mohamed Adel Eltomey,Ghada Elsaed Awad,Amr Ahmed Mubarak

doi:10.1186/s43055-019-0036-5

Abstract

BackgroundTo study the ability of non-contrast MR portography using time-spatial labeling inversion pulse (T-SLIP) as a non-invasive contrast-free imaging modality to delineate different portal vein pathological conditions.The study included 25 patients with known history of portal vein disease and another 25 age-matched patients with normal portal vein. Both groups were examined by respiratory-triggered non-contrast MR portography using time-spatial labeling inversion pulse technique. Image quality was assessed first, and findings of diagnostic scans were compared to color duplex ultrasonography and selectively in those with diseased portal vein to portal-phase images of dynamic contrast-enhanced MRI.ResultsSignificant relation was found between breathing regularity and image quality in T-SLIP sequence, with diagnostic scans sensitivity and specificity of 89.29% and 86.21%, respectively, for diagnosis of different portal vein pathological conditions.ConclusionsNon-contrast MR portography is a useful technique for diagnosis of portal vein pathology in carefully selected patients.

Highlights

To study the ability of non-contrast Magnetic resonance (MR) portography using time-spatial labeling inversion pulse (T-SLIP) as a non-invasive contrast-free imaging modality to delineate different portal vein pathological conditions
Portal vein assessment has been traditionally carried out using different imaging modalities including color duplex ultrasonography, contrast-enhanced computed tomography (CT), and contrast-enhanced magnetic resonance imaging (MRI) as well as different diagnostic invasive angiographic techniques including percutaneous transhepatic portography and splenoportography [2]
In conclusion, based on our findings non-contrast MR portography using time-spatial labeling inversion pulse is considered a promising, helpful non-invasive contrastfree diagnostic tool for demonstrating different portal vein pathological conditions with diagnostic scans obtained in carefully selected patients who breathe regularly and tolerate long scan times

Summary

Introduction

To study the ability of non-contrast MR portography using time-spatial labeling inversion pulse (T-SLIP) as a non-invasive contrast-free imaging modality to delineate different portal vein pathological conditions. The study included 25 patients with known history of portal vein disease and another 25 age-matched patients with normal portal vein Both groups were examined by respiratory-triggered non-contrast MR portography using time-spatial labeling inversion pulse technique. Portal vein assessment has been traditionally carried out using different imaging modalities including color duplex ultrasonography, contrast-enhanced computed tomography (CT), and contrast-enhanced magnetic resonance imaging (MRI) as well as different diagnostic invasive angiographic techniques including percutaneous transhepatic portography and splenoportography [2]. Each of these techniques has certain drawbacks: the operator-dependent nature of ultrasound and its suboptimal performance in patients with poor acoustic window, the risk of ionizing radiation and contrast-induced nephropathy and allergic reactions in CT, and the risk of. In the flow-in method, selective inversion recovery tagging pulse is used for suppression of blood signal when it is placed on the vessels of no interest like aorta and inferior vena cava, giving a black

Methods

Results

Discussion

Conclusion