Abstract
The aim of this work was the study of indicators characterizing the local immunity in patients with various forms of glomerulonephritis by presence of herpesviral infection.
 Materials and methods. A quantitative estimation of the content of sIgA and MCP-1 in urine of 47patients with glomerulonephritis and 10 apparently healthy individuals was conducted.
 Results. The decrease of sIgA level and reliable increase ofMCP-1 level were observed in urine of patients with glomerulonephritis. There was a significant increase in the level of these indices in hormone-resistant patients with nephrotic form of glomerulonephritis; in patients with severe course of the disease and also in the absence of remission. More such changes were found in children with active (reactivated) herpesviral infections.
 Conclusion. There has been confirmed the importance of the study of immunologic parameters in the urine of patients with glomerulonephritis to characterize immunopathological process in the kidney and prognosis of the disease.
Talk to us
Join us for a 30 min session where you can share your feedback and ask us any queries you have
Disclaimer: All third-party content on this website/platform is and will remain the property of their respective owners and is provided on "as is" basis without any warranties, express or implied. Use of third-party content does not indicate any affiliation, sponsorship with or endorsement by them. Any references to third-party content is to identify the corresponding services and shall be considered fair use under The CopyrightLaw.