Abstract
The review presents an analysis of modern methods and instruments for performing nonspecific detection of pathogenic biological agents in environmental objects. Discussed are technological characteristics of application of these methods for the detection of biological substances of protein nature in samples. The spectrum of means for non-specific PBA detection includes home-produced and foreign field devices based on protein contamination indication using various colorimetry variants. Technologies for remote and direct monitoring of environment for the presence of aerosols of biological nature are represented by hybrid lidar systems (biolidars) and biodetectors. For PBA nucleic acids tracing, the complexes based on DNA molecule binding with fluorophore with further fluorescence detection are described. Given are the examples of chemiluminescent analysis application in the developed automatic impurity detectors, as well as systems using bioluminescence. Based on the literature data analysis, put forward is a possible algorithm for indication of pathogenic biological agents when carrying out monitoring of the environment in zones of possible emergency situation occurrence and mass events holding.
Highlights
The review presents an analysis of modern methods and instruments for performing nonspecific detection of pathogenic biological agents in environmental objects
Technologies for remote and direct monitoring of environment for the presence of aerosols of biological nature are represented by hybrid lidar systems and biodetectors
К недостаткам сигнализатора автоматический сигнализатор примесей (АСП) относятся ограниченный спектр обнаруживаемых биоаэрозолей из-за низкого уровня пероксидазной активности или ее отсутствия у ряда биологических агентов (БА), ухудшение порога чувствительности при обнаружении биоаэрозоля в запыленной атмосфере, а также большой расход индикаторных средств
Summary
The review presents an analysis of modern methods and instruments for performing nonspecific detection of pathogenic biological agents in environmental objects. Одной из главных задач биомониторинга объектов окружающей среды в зонах возможного возникновения чрезвычайных ситуаций (ЧС), а также в местах проведения массовых мероприятий является обнаружение веществ белковой природы, что определяет необходимость разработки экспрес сных методов индикации и создания на их основе современных технических средств для своевременного обеспечения санитарно-гигиенических и противо эпидемических мероприятий.
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