Abstract
PurposeNon-severe nocturnal hypoglycemic events (NSNHEs) are hypoglycemic events that occur during sleep but do not require medical assistance from another individual. This study was conducted to better understand the NSNHEs as patients actually experience them in their daily life, and how they impacted functioning and well-being.MethodsNine focus groups were held in four countries with diabetics (Type 1 and Type 2) who had experienced an NSNHE within the previous month: France (2 groups); Germany (2 groups); United Kingdom (2 groups); and United States (3 groups). These groups were audio-taped, translated to English where applicable, and analyzed thematically.ResultsSeventy-eight people with diabetes participated in the focus groups: 41 (53 %) were female and 37 (47 %) were male; 24 (31 %) had Type 1 diabetes, and 54 (69 %) had Type 2 diabetes. Participant reports were grouped into several major themes: next day effects, symptoms, sleep impacts, social impacts, corrective action, practical management, feelings about NSNHEs, and work impacts.ConclusionsPeople with both Type 1 and Type 2 diabetes experience NSNHEs. The range of impact on these patients is wide, from very mild to severe with a majority of participants experiencing strong impacts that limit their daily functioning. This finding suggests that NSNHEs are more impactful than previously believed.
Highlights
Hypoglycemia in general, including non-severe nocturnal hypoglycemic events (NSNHEs), is a frequent complication of anti-diabetic medication
Purpose Non-severe nocturnal hypoglycemic events (NSNHEs) are hypoglycemic events that occur during sleep but do not require medical assistance from another individual
The range of impact on these patients is wide, from very mild to severe with a majority of participants experiencing strong impacts that limit their daily functioning
Summary
Hypoglycemia in general, including non-severe nocturnal hypoglycemic events (NSNHEs), is a frequent complication of anti-diabetic medication. NSNHEs are rarely studied for their impacts on patient function or well-being and may be misunderstood and underreported by healthcare practitioners [1]. NSNHEs are hypoglycemic events that occur during sleep but do not require medical assistance from another individual. A review of the literature reveals that the majority of research that has been conducted has focused on either severe hypoglycemic events during sleep, or laboratory-induced NSNHEs. The conclusions drawn from these investigations are not generalizable to the everyday life of patients with diabetes. There is a lack of data specific to how NSNHEs are experienced by patients, and their impacts or consequences. There is evidence of sleep-related hypoglycemiaassociated autonomic failure among those with Type 1 diabetes that result in a failure of the patient to awaken
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