Non-Newtonian droplet-based microfluidics logic gates.

Abstract

Droplet-based microfluidic logic gates have many applications in diagnostic assays and biosciences due to their automation and the ability to be cascaded. In spite of many bio-fluids, such as blood exhibit non-Newtonian characteristics, all the previous studies have been concerned with the Newtonian fluids. Moreover, none of the previous studies has investigated the operating regions of the logic gates. In this research, we consider a typical AND/OR logic gate with a power-law fluid. We study the effects of important parameters such as the power-law index, the droplet length, the capillary number, and the geometrical parameters of the microfluidic system on the operating regions of the system. The results indicate that AND/OR states mechanism function in opposite directions. By increasing the droplet length, the capillary number and the power-law index, the operating region of AND state increases while the operating region of OR state reduces. Increasing the channel width will decrease the operating region of AND state while it increases the operating region of OR state. For proper operation of the logic gate, it should work in both AND/OR states appropriately. By combining the operating regions of these two states, the overall operating region of the logic gate is achieved.