Non-muscle invasive transitional cell carcinoma of the distal ureter and bladder with lung metastasis: A case report and literature review

Abstract

INTRODUCTIONNon-muscle invasive transtitional cell carcinoma (TCC) with metastases is exceedingly rare. PRESENTATION OF CASEWe report the case of a 78-year old man with an incidental finding of a non-muscle invasive TCC of the left distal ureter during treatment for Duke's B Colon cancer. Following laparoscopic nephro-ureterectomy (LNU) he had two further superficial recurrences in the bladder over a 14-month period which underwent transurethral resection (TUR). On surveillance imaging for his colorectal cancer follow-up a lung nodule was detected and video-assisted thoracic surgical (VATS) resection of the lesion showed it to be TCC in origin. He was referred to oncology for chemotherapy and remains clinically well. DISCUSSIONA Literature search found only three other such cases and the ureteric TCC is the most likely source of the metastasis. CONCLUSIONThis occurrence is exceedingly rare.