Abstract
Through whole-genome sequencing analysis, we identified non-Leishmania parasites isolated from a man with a fatal visceral leishmaniasis–like illness in Brazil. The parasites infected mice and reproduced the patient’s clinical manifestations. Molecular epidemiologic studies are needed to ascertain whether a new infectious disease is emerging that can be confused with leishmaniasis.
Highlights
Through whole-genome sequencing analysis, we identified non-Leishmania parasites isolated from a man with a fatal visceral leishmaniasis–like illness in Brazil
Dermal lesions known as post–kalaazar dermal leishmaniasis (PKDL) have rarely been reported in Brazil [13], and the clinical aspect of the disseminated papular skin lesions on this patient differed from the clinical presentation of PKDL
Non-Leishmania parasites isolated from 2 patients with visceral leishmaniasis–like illness used for whole-genome sequencing, Brazil*
Summary
Through whole-genome sequencing analysis, we identified non-Leishmania parasites isolated from a man with a fatal visceral leishmaniasis–like illness in Brazil. The Study During 2011–2012, we characterized 2 parasite strains, LVH60 and LVH60a, isolated from an HIV-negative man when he was years old and years old (Table; Appendix, https:// wwwnc.cdc.gov/EID/article/25/11/18-1548-App1.pdf). Non-Leishmania parasites isolated from 2 patients with visceral leishmaniasis–like illness used for whole-genome sequencing, Brazil*
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