Abstract

A robust means of fabricating skin-penetrating and compatible nanocarriers comprising poly(D, L-lactide-co-glycolide) is reported. The resultant nanocapsules have the ability to load biologically active ingredients and selectively release them through the epidermis lipid layer. Their release of genistein (left figure) is determined to be diffusion-controlled, and they are shown to successfully deliver molecules, such as nile red (right figure), into biopsied skin samples. Detailed facts of importance to specialist readers are published as ”Supporting Information”. Such documents are peer-reviewed, but not copy-edited or typeset. They are made available as submitted by the authors. Please note: The publisher is not responsible for the content or functionality of any supporting information supplied by the authors. Any queries (other than missing content) should be directed to the corresponding author for the article.

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