Abstract
Background A majority of patients (85-90%) diagnosed with pancreatic cancer has advanced disease at the time of diagnosis with a dismal prognosis. Pain is a common symptom in patients (60-90%) with advanced disease. Pain is neuropathic and inflammatory, resulting from both tumour expansion and tumour invasion of the celiac and mesenteric plexus. Opioids have side effects and may not be sufficient while celiac plexus neurolysis is an invasive procedure, despite the questionable results reported. Currently, HIFU (high intensity focused ultrasound) an emerging procedure completely no invasive, has been gaining wide acceptance not only for treating neoplasm but for symptom’s relief also.
Highlights
A majority of patients (85-90%) diagnosed with pancreatic cancer has advanced disease at the time of diagnosis with a dismal prognosis
Pain is a common symptom in patients (60-90%) with advanced disease
Endoscopic placement of a metal stent followed by HIFU treatment was considered the best suitable option
Summary
A majority of patients (85-90%) diagnosed with pancreatic cancer has advanced disease at the time of diagnosis with a dismal prognosis. Pain is a common symptom in patients (60-90%) with advanced disease. Pain is neuropathic and inflammatory, resulting from both tumour expansion and tumour invasion of the celiac and mesenteric plexus. Opioids have side effects and may not be sufficient while celiac plexus neurolysis is an invasive procedure, despite the questionable results reported. HIFU (high intensity focused ultrasound) an emerging procedure completely no invasive, has been gaining wide acceptance for treating neoplasm but for symptom’s relief
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