Abstract
The Sri Lanka Journal of Psychiatry (SLJP) is a peer-reviewed, open access journal published bi annually by the Sri Lanka College of Psychiatrists.The Journal publishes original papers, brief reports including case reports and commentaries relevant to psychiatry and allied sciences. The Sri Lanka Journal of Psychiatry is committed to maintaining and conforming to the editorial and ethical standards recommended by the International Committee of Medical Journal Editors.The CoverCover “The perks of working as a psychiatrist in the periphery”. – Nilaveli beach early in the morning as captured by Dr Sumudu Godawita, Consultant Psychiatrist, Trincomalee.
Highlights
Model support the use of Repetitive transcranial magnetic stimulation (rTMS) in adults with MDD, who have failed to respond to a single trial of antidepressant medication
Blumberger et al described intermittent theta burst stimulation as a newer form of rTMS that can be delivered in 3 min, as opposed to the 37.5 min standard 10 Hz treatment session
Voigt et al used the lifetime Markov stimulation model to compare the direct costs and quality adjusted life years (QALYs), between rTMS and medication therapy, among a group of patients who were newly diagnosed with major depressive disorder and who had failed to benefit from one pharmacotherapy trial
Summary
Model support the use of rTMS in adults with MDD, who have failed to respond to a single trial of antidepressant medication. They conducted a randomized, multicentre, non-inferiority clinical trial on patients diagnosed with a treatment-resistant major depressive episode or those who could not tolerate at least two antidepressants in the current episode. They reported that iTBS (n=193) was non-inferior to 10 Hz rTMS (n=192) for the treatment of depression.
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