Abstract
Lymphomas are malignant neoplasms. They are classied into Hodgkin’s and Non-Hodgkin’s lymphoma. NHL develops primarily within the lymph nodes, however approximately 24% of NHL affect the extranodal sites. There is increased prevalence of NHL in immunocompromised individuals. NHLis a group of diverse malignancies affecting organs and tissues that do not contain lymphoid cells. The signs and symptoms of NHL are tooth mobility, localized swelling with ulcer, unexplained dental pain, or ill-dened lytic osseous changes. In the head and neck the primarily NHL is present in Waldeyer’s ring, Oral mucosa, Salivary glands, Laryngeal tissue, Paranasal sinuses and Osseous structures.NHL can be a B-cell or T-cell as cell of origin. Oral NHL are commonly Diffuse B- cell type. Immunohistochemistry (IHC) plays a vital role in distinguishing the cell types and differential diagnosis. The mainstream treatment of Diffuse large Bcell lymphoma is chemotherapy and alternate treatment is surgery. Here, we discuss a rare case of Non - Hodgkin’s lymphoma of the buccal mucosa.
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